Structure and Composition ofÂ Parlodel
1 tablet contains bromocriptine mesylate 2.5 mg; per pack 30 pcs.
Indications for use ofÂ Parlodel
Prolactin-dependent menstrual disorders and female infertility, polycystic ovarian syndrome, anovulatory cycles (in addition to antiestrogens), premenstrual syndrome, hyperprolactinemia in men prolactinomas, acromegaly, suppression of lactation (for medical reasons), postpartum breast engorgement beginning postnatal mastitis , mastalgia and other forms of benign breast disease, Parkinson’s disease.
Suppression of lactation:
– Prevention or suppression of lactation in postpartum period for medical reasons;
– Prevention of lactation after abortion; – During post-natal pathological hypertrophy of the mammary glands;
– The threat of puerperal mastitis.
Benign breast diseases:
– Mastalgia (alone or in combination with premenstrual syndrome or the presence of benign nodular or cystic changes);
– Benign cystic and / or nodular disease, in particular breast Fibrocystic breast disease.
Contraindications ofÂ Parlodel
Hypersensitivity, malignant mammary tumors, hypertension (uncontrolled during pregnancy, postpartum), ischemic heart disease and other serious cardiovascular diseases, mental illness (including history).
Side effects ofÂ Parlodel
Dry mouth, nausea, vomiting, constipation, dizziness, headache, drowsiness, weakness, confusion, agitation, hallucinations, dyskinesia, leg muscle cramps, cold upper and lower extremities, orthostatic hypotension, collapse, stuffy nose, loss of hair, allergic skin reactions. With long-term treatment of Parkinson’s patients with high doses – pleural effusion, pleural, pulmonary or retroperitoneal fibrosis. In pregnant women rarely observed the development of hypertension, myocardial infarction, seizures, stroke, mental disorders.
Dosing and Administration ofÂ Parlodel
Inside, during a meal. At 1,25-40 mg per day.
Interaction ofÂ Parlodel
Macrolides can increase the concentration in plasma. Portability is reduced on the background of alcohol.
In the postpartum period, it is not recommended to combine with vasoconstrictor drugs, or ergot alkaloids.
It is necessary to periodically monitor blood pressure; if developing hypertension, severe headache, blurred vision or neurointoxication symptoms, treatment should be stopped. It should be particularly careful when driving vehicles or operating machinery. Parlodel can restore reproductive function.
Dosages ofÂ Parlodel
Parlodel should always be taken with food.
Menstrual irregularities, infertility in women: In half a tablet, 2 or 3 times a day; if this is not sufficient, it is necessary to gradually increase the dose of one tablet 2 or 3 times a day.
Treatment will continue until the return of menstruation and / or ovulation to normal.
Premenstrual symptoms: Treatment started 14 days cycle by half a tablet a day: at half the dose increased tablets per day, two times a day one tablet, to restore the menstrual cycle.
Male hypogonadism: For half tablets 2 or 3 times a day, with gradual dose increases to 2-4 tablets per day.
Prolactinoma: Tablets By half 2 or 3 times a day, with gradual dose increases to several tablets per day as needed to sufficiently suppress the plasma level of prolactin.
Acromegaly: Initially for half tablets 2 or 3 times a day, with gradual dose increases to 4-8 tablets per day depending on the clinical response and tolerability.
Suppression of lactation: Initially half a tablet at breakfast and dinner, then one tablet twice a day for 14 days.
To prevent the start of lactation: treatment should be started within a few hours after birth or abortion, but only after stabilization of vital signs. After 2 or 3 days after cessation of treatment is sometimes observed small milk secretion. It can be stopped and resumed treatment similar dose of the drug for another week.
Hypertrophy of the breasts in the postpartum period: A single tablet at the reception: the reception can be repeated after 6-12 hours if necessary without undue suppression of lactation.
Postnatal mastitis early phase: The same dosage as for the suppression of lactation. If necessary, a scheme can be added antibiotic treatment.
Benign breast disease: For half tablet 2-3 times a day, gradually increasing the dose to 2-3 tablets per day.