Detrol La (Tolterodine)

Drug Information: Indications, Side Effects, Warnings

Category: Urinary Tract


Generic Detrol LA is used for treating overactive bladder with symptoms of urinary frequency, urgency, and Detrol La

Brand(s): Roliten OD

Manufacturer: Ranbaxy

Effects on the body:
Reduces bladder contractile activity and reduces salivation. Reduces detrusor pressure, suppresses involuntary discharge of urine increases the interval between urination, increases urine output, contributes to the disappearance or weakening of urgency. The therapeutic effect is achieved within 4 weeks.

Indications for use:

Bladder hyperreflexia (hyperactivity, instability), manifested by frequent Urinary urgency or incontinence.


Adult inside of 2 mg 2 p / day. With the development of side effects, and patients with impaired renal function – 1 mg 2 p / day. After 6 months it should assess the need for further therapy. The recommended dose for patients with impaired liver and / or kidney disease is 1 mg 2 p / day.

Caution should be used: for significant violations of the outflow of urine from the urinary retention, obstructive conditions of the SS, kidney and liver damage, neuropathy, irreducible hernia. Before treatment it should exclude organic causes frequent and urgency.

Side effects:

Side effects associated with anticholinergic effects: dry skin and mucous membranes, decreased lacrimation; rare accommodation disturbances, urinary retention.

At SS: dyspepsia, constipation, abdominal pain, flatulence, and vomiting.

On the central nervous system, mental and visual organs: headache, xerophthalmia, drowsiness, nervousness, paresthesia; rare – impaired consciousness.

Other: rarely – pain in the chest, AR.


Urinary retention, angle-closure glaucoma can not be disinfected, myasthenia gravis, severe ulcerative colitis, megacolon, hypersensitivity to tolterodine.

Accommodation disturbances and tenesmus. There are hallucinations, severe agitation, convulsions, respiratory failure, tachycardia, urinary retention, mydriasis.
– Gastric lavage and activated charcoal. When expressed central anticholinergic effects (in Vol. H. Hallucinations) – physostigmine; in convulsions or an excited expression – benzodiazepines, tachycardia – BAB.


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