Oxytrol treats symptoms of overactive bladder via reduction of muscle spasms of the bladder and urinary tract.
Active substance: Oxybutynin (main ingredient).
Pharmacological group of Oxytrol
The nosological classification (ICD-10) of Oxytrol
N31.2 neurogenic bladder weakness, not elsewhere classified
R32 Urinary incontinence unspecified
Z100 * CLASS XXII Surgical practice
Pharmacology of Oxytrol
Mode of action – antispasmodic, myotropic.
Oxytrol Does m-cholinergic receptors. Oxytrol Eliminates spasms and reduces the tone of smooth muscles: stomach, bile and urinary tract, the uterus, particularly well relaxes the smooth muscles of the bladder. Patients with neurogenic bladder, Oxytrol increases its capacity, relaxes and reduces the incidence of detrusor contractions, holding back the urge and reduces the number of urination (involuntary and voluntary). Oxytrol can be used for a long time – from 1 month to 2 years.
Indications of Oxytrol
Neurogenic bladder, idiopathic unstable bladder (with frequent urination, urinary incontinence, urination, dysuria and other symptoms); hyperreflexia and detrusor dysfunction; nocturnal enuresis, and neurogenic bladder disorders in children older than 5 years.
Contraindications of Oxytrol
Hypersensitivity, glaucoma (open-and zakryto-), gastrointestinal obstructive disorders, paralytic ileus, the expansion of the colon (including toxicity complicated by ulcerative colitis), severe colitis, myasthenia gravis (including myasthenia gravis), obstructive uropathy cause, intestinal atony in elderly and debilitated patients, acute bleeding instability cardiovascular parameters, pregnancy, lactation, children’s age (up to 5 years).
Pregnancy and breast-feeding
Category effects on the fetus by FDA – B.
Side effects of Oxytrol
Dry mouth, nausea, vomiting, constipation, flatulence, decreased motility of the stomach and intestines, urinary disorders (including urine retention), palpitations, tachycardia, vasodilatation, weakness, dizziness, drowsiness or insomnia, anxiety, hallucinations, production decline lacrimal fluid, mydriasis, increased intraocular pressure, paralysis of accommodation, blurred vision (amblyopia), decreased sweating, impotence, suppression of lactation, allergic reactions (rash).
Interaction of Oxytrol
Alcohol and other sedatives increase dizziness and drowsiness.
Overdose of Oxytrol
Symptoms: CNS arousal (anxiety, tremors, irritability, convulsions, delirium, hallucinations), flushing, fever, nausea, vomiting, tachycardia, hypo- or hypertension, respiratory failure, paralysis, coma.
Treatment: maintenance of respiratory function, induction of vomiting, gastric lavage; possible use of activated charcoal and laxatives; to reverse symptoms of anticholinergic intoxication administered physostigmine; with hyperpyrexia – cold packs, including ice, alcoholic wiping.
Dosing and Administration of Oxytrol
Inside, and food. The dosage and administration schedule individual. Usually – 5 mg (Table 1). 3.2 times (up to 4) per day for adults and 2 times (less than 3) per day for children older than 5 years; the maximum dose – 20 mg, and 15, respectively. Older children and possible appointment to the initial dose of 2.5-3 mg 2 times a day with a gradual increase to normal. If nocturnal enuresis – the last intake before bedtime.
To use caution: when neuro dystonia, liver and kidney diseases, hyperthyroidism, coronary artery disease, congestive heart failure, tachycardia, arrhythmia, hypertension, benign prostatic hyperplasia (especially in the initial stages), ulcerative colitis, diaphragmatic hernia (including related gastroesophageal reflux disease), diarrhea accompanying incomplete intestinal obstruction (especially in patients with ileo or colostomy) in the elderly. During treatment is not recommended to drive and deal with others. Activities that require high concentration and associated with the risk of his life (may develop dizziness and blurred vision). It should be borne in mind that high ambient temperatures often provokes fever and heart failure (decreased sweating) against oxybutynin.