Proscar (Finasteride) is used to treat Benign prostatic hyperplasia (BPH).
Pharmacological groups of Proscar
Drugs affecting the metabolism of the prostate gland and correctors urodynamics
The nosological classification (ICD-10) of Proscar
N40 Hyperplasia of prostate
Structure and Composition of Proscar
1 tablet contains 5 mg finasteride; in blisters of 14 pcs., in box 1 or 2 packaging.
Pharmacologic effect of Proscar
Mode of action – anti-androgenic.
The drug inhibits 5-alpha reductase, reduces the biosynthesis of dihydrotestosterone.
Clinical pharmacology of Proscar
The suppression of DHT formation accompanied by a decrease in prostate volume, an increase in maximum urinary flow rate, a decrease in obstruction of urinary tract symptoms.
Indications for use of the drug
Benign prostate hyperplasia in order to: reduce the size of prostate; improve urine flow and decrease the symptoms associated with hyperplasia; reduce the risk of acute urinary retention requiring catheterization or surgery including transurethral resection of the prostate (TURP) and prostatectomy.
Contraindications of Proscar
Hypersensitivity, children’s age.
Side effects of Proscar
Sexual dysfunction (impotence, decreased libido, decrease in the volume of ejaculate).
From the reproductive system: testicular pain, impotence, decreased libido, ejaculation disorders, reduction of volume of ejaculate.
From endocrine system: increased and painful breast.
Allergic reactions: rash, pruritus, urticaria, angioneurotic edema of the lips and face.