Drug Information: Indications, Side Effects, Warnings
Category: Â Men’s Health, Hypertension
Generic Hytrin is used for treating high blood pressure. It used for treating signs and symptoms of benign prostatic hyperplasia (BPH) too.
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Drugs affecting the metabolism in the prostate gland and proofreaders urodynamics
Nosological classification (ICD-10):
I10 Essential (primary) hypertension
I15 Secondary hypertension
N40 prostatic hyperplasia
Pharmacological action – alpha adrenolytic.
Selectively blocks postsynaptic alpha 1-adrenergic receptors, reduces the tone of smooth muscles of the prostate gland, blood vessels.
In patients with BPH normalizes urination (alpha1-adrenoceptor blockade of smooth muscle of the triangle and the bladder neck, the proximal urethra, prostate). The drug causes expansion of resistive (arterial) blood vessels, reduces blood pressure and systemic vascular resistance. Reduces the pre- and afterload on the heart. Does not cause severe tachycardia (Unlike the non-selective alpha 1 blockers and alpha 2-adrenergic receptors). Has a lipid-lowering activity.
– Quickly and completely absorbed in the digestive tract.
– Cmax plasma levels achieved after 1 hour.
– Intensively binds to blood proteins. T1 / 2 – 12 hours.
– It is metabolized in the liver.
– About 10% is excreted unchanged in the urine and 20% – through the intestines; remainder is excreted in the form of metabolites.
Indications of the drug:
Prostate adenoma, arterial hypertension.
Asthenia, breach of clarity of vision, nasal congestion, nausea, peripheral edema, tendency to weight gain in patients; lower hematocrit, hemoglobin, leukocyte, total protein and albumin levels.
Dosage and administration:
Inside. Hypertension: start with receiving the lowest dose (1 mg), and then it is increased to 1.5 mg / day in 1-2 reception. The maximum daily dose is 20 mg.
Prostate adenoma: first taking 1-2 mg, then – 5 mg (clinical effect is achieved). In case of cancellation of treatment, reduce the dose gradually (over several days).
Storage conditions of the preparation:
The temperature is not above 40 Â° C.
Keep out of the reach of children.
Shelf life: 3 years.
Do not uses after the expiration date, printed on the packaging.
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