Motilium: Instructions for use

Pharmachologic effect

Motilium is a stimulant of intestinal peristalsis, has anti-emetic effect. The active substance Motilium is Domperidone, which is characteristic of the effect of some antipsychotic drugs. In contrast, it does not cause extrapyramidal side effects ( dystonia, tremor, chorea, athetosis, akathisia, teak, myoclonus, stereotypes). Also found that increases prolactin domperidone (peptide hormone that stimulates milk production). Motilium increases the tone and the pressure on the sphincter of the lower esophagus. In the production of gastric juice is not affected by the drug.

Product: Producing a tablet conventional, lingual (resorption), suspension

Motilium 10mg 10 Pack

Motilium 10mg 10 Pack

Indications for use

Motilium is prescribed for instructions on:

dyspeptic disorders caused by slow gastric emptying, reflux, gastroesophageal, esophagitis (vomiting, bloating, fullness and bloating, belching, heartburn, nausea, epigastric pain), nausea, vomiting, triggered by the use of dopamine agonists patients suffering from Parkinson’s disease (eg , L-dopa, bromocriptine), nausea and vomiting organic, infectious, functional origin, nausea and vomiting caused by radiation therapy, diet disorder medication. Motilium is effective for children – vomiting cyclic vomiting syndrome, gastroesophageal reflux, gastric motility disorders of other children.


Motilium on instructions do not apply if: gastrointestinal perforation, obstruction of its mechanical nature, with pituitary tumors, produce prolactin, bleeding gastrointestinal, in case of hypersensitivity to the active and auxiliary substances of the drug. For these indications Motilium should not be used simultaneously with ketoconazole, erythromycin, voriconazole, fluconazole, amiodarone, clarithromycin, telithromycin. During lactation, pregnancy is not recommended to use the drug.

Side effects

Motilium may cause amenorrhea, hyperprolactinemia (a disease in which increased levels of prolactin), gynecomastia, reversible extrapyramidal pathology in children (after the abolition of the means tested), disorders of the gastrointestinal tract, spastic bowel reduction, allergic reactions. Children under one year Motilium may cause neurological disorders. Overdose may cause disorientation, drowsiness, extrapyramidal disorder (most often occur in children).

For the treatment of extrapyramidal disorders can be assigned to anticholinergic agents, drugs for the treatment of Parkinson’s disease. Begin to eliminate the symptoms of an overdose of a gastric lavage procedure.