Frumil (co-amilofruse)

Drug Information: Indications, Side Effects, Warnings

This particular diuretic is not one diuretic but instead two: it contains two active ingredients which are amiloride and furosemide. The latter belongs to a class of loop diuretics while amiloride belongs to a class of potassium-sparing diuretics. This drug is produced in a form of tablets with two different quantitative composition: with 40g or 20 g of furosemide. Therefore Frumil should be prescribed for the peroral administration.

K-sparing, or potassium-sparing diuretic are needed for the proper regulation of the process of diuresis but with saving the optimum potassium level. Such medical conditions which require conservation of potassium are nephrosis, oestrogen therapy, congestive heart failure, corticosteroid therapy, and cirrhosis with such complication as ascites.

It is worth to note that Frumil is strongly not recommended for those younger 18 years old, that is due to the limited information about its efficacy and safety for such age group. As for the adult the dosage must be counted based on patient’s response with monitoring of urea and serum electrolytes. Main contradictions include breastfeeding, hypersensitivity to the Frumil active ingridients, renal failure, anuria, hypovlaemia, various stages of hyperkalaemia, Addson’s disease.

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