What is Vytorin 10 40 used for? Cost Of Vytorin.


Generic Name: Ezetimibe and simvastatin


Vytorin is a combination of two medications, simvastatin and ezetimibe.  Simvastatin is a member of a collection of drugs termed HMG CoA reductase inhibitors or statins.  Ezetimbe is able to decrease the amount of cholesterol that is absorbed by a person’s body.

The duo of medications are able to reduce the levels of low density lipoprotein/LDL (bad cholesterol) and triglycerides within the blood and the medication is also able to improve the levels of high density lipoprotein. HDL (good cholesterol).


Grapefruits and its byproducts have been known to interact with Vytorin in a way that is potentially dangerous in regards to its effects.  While Vytorin is a part of your treatment regimen, grapefruit (in all forms) is not to be ingested.

If a patient is taking either colestipol, colesevelam or cholestyramine, the doses should be scheduled a part from those of Vytorin.  Vytorin should be taken either 4 hours after or 2 hours before any of the listed medication are taken.

The consumption of alcohol can lead to an increase in levels of triglyceride which can increase a patient’s risk of liver disease.

Foods that are high in cholesterol or fat should not be consumed because they will simply nullify the effects of the medication.

Vytorin can have adverse reactions for individuals that are of Chinese decent and/or older than 65 years of age.

Vytorin has the ability to cause a condition that results in the breakdown of tissue within skeletal muscle that will lead to kidney disease.  The condition is more likely to occur within people who are advanced in age along with individuals that currently suffer from kidney disease or have an underactive thyroid (hypothyroidism).

Should a woman become pregnant, the medication is to be stopped immediately and her primary care physician.  Vytorin carries an FDA pregnancy category of X because it is known to cause birth defects or harm to an unborn child.  Therefore effective birth control need to be taken regularly by any woman that is still within the range of child bearing age.  It is also possible to the drug to pass through breast milk, therefore mothers of infants are highly advised to explore alternative options.

 Before Beginning Vytorin

If you are allergic to simvastatin or ezetimibe, Vytorin is not to be added to your treatment program.

It is imperative that your primary care physician is made aware if you are currently taking any of the following medications:

  • Cyclosporine
  • Danazol
  • Gemfibrozil
  • Nefazodone
  • Antibiotics
  • Antifungal medications
  • Medications used to treat hepatitis C
  • AIDS/HIV medications

Additionally, to ensure your safety, your doctor should be made aware to the fact that you currently suffer from any of the following:

  • History of liver disease
  • History of kidney disease
  • Untreated or uncontrolled seizures
  • A thyroid disorder
  • Alcoholism
  • Low blood pressure
  • An imbalance of electrolytes


Drug Interactions

The following medications are able to increase a person’s risk for muscle problems that are quite serious when taken in conjunction with Vytorin:

  • Cyclosporine
  • Danazol
  • Gemfibrozil
  • Nefazodone
  • Antibiotics
  • Antifungal medications
  • AIDS/HIV medications
  • Hepatitis C medications

Your health care professional should be made aware if you are taking any of the following, the combination can result in unnecessary side effects or complications:

  • Amiodarone
  • Amlodipine
  • Diltiazem
  • Dronedarone
  • Ranolazine
  • Verapamil


Side Effects

Should you discover that you are allergic to Vytorin, seek emergency medical attention immediately. The following are symptoms of an allergic reactions:

  • Swelling of the throat, lips or face
  • Difficulty breathing
  • Hives

It is also important to contact a doctor should the following side effects present themselves:

  • Severely reduced urination
  • Rapid weight gain
  • Swelling
  • Nausea
  • Upper stomach pain
  • Loss of appetite
  • Unusual tiredness
  • Darkened urine
  • Stools that are clay colored
  • Jaundice (yellowed eyes or skin)

The most common of the side effects that are associated with Zocor are as follows:

  • Headache
  • Constipation
  • Cold symptoms

Purchasing Vytorin

There are online retailers that are based in Canada health, Greece and the United Kingdom that will allow consumers to purchase the medication without a prescription and it can be delivered overnight.  There are an increasing number of online pharmacies that are requiring a prescription in order for an order to be placed.   Typically, Vytorin is sold in pills that are 10mg to 80mg and quantities that range from 30 to 90 pills.  The average cost of Vytorin is $1.10  per pill.