Monoket: treating angina

Monoket is a medicine used for preventing and treating angina. The drug works by making blood vessels wider. It decreases heart’s workload and softens pain in the chest.

Monoket uses

Brand(s):Monit, Mononit, Plodin, Imdur, Conpin


Clinic-pharmacological group:

Cardio-vascular medicine.

Composition, structure and packing:

White tablets, film-coated, round-shaped.

Basic ingredient:

20 mg isosorbide mononitrate

The composition of the coating film:

Talc, lactose, starch, aluminum stearate.

Basic ingredient:

20 mg isosorbide mononitrate


Consult with the cardiologist before starting using Monoket to avoid overdose and progressing of the decease. Dose of medicine has to be measure by a specialist according to medical indications of the patient. It is forbidden to use the drug more or for a longer term than it was directed and follow the instructions of the cardiologist. The specialist can replace the standard dose with your individual one to achieve better results of your treatment course. The main ingredient of the medicine is produced by many companies and not all of them are taken identically.

Usually the recommended dose is 20 mg two times daily. The possible dose for people of small stature might be 5 mg but it should be increased at the second day of the course. The doctor may prescript an asymmetric dose schedule to avoid tolerance development.

The skipped dose must be taken as soon as you recall it. If the time of your next dose is close do not take the missed one. Do not use extra doses to avoid overdose. Taking isosorbide mononitrate must not be given up suddenly as it causes severe angina attack. Read the instruction before starting the therapy.


An overdose of the medicine can be lethal. Call for ambulance if you suspect taking too much tablets. Since the drug works by widening the arteries and veins the results of overdose are venous pooling, decreased cardiac output, hypotension. The symptoms of overdose are increased blood pressure, throbbing headache, unconsciousness, hard or double vision, vomiting, hard breathing, diaphoresis. The overdose may lead to coma and death. There is no certain information of what dose is fatal. One harmful effect can occur in case of combining Monoket with arterial vasoconstrictors. Consult the doctor to know more about combining medications during the therapy.

Side effects

The most frequent side effect of taking Monoket is a headache which was also caused by stopping supervised clinically controlled therapy. Other common side effects are:

  • Dizziness
  • Weakness
  • Tiredness
  • Pain
  • Increased nausea
  • Allergy
  • Cough
  • Chest pain

Indications for use

Monoket is recommended for treatment of angina pectoris.


Monoket interacts with other medicines such as Cardizem, Verelan, Isoptin, Dilacor. Combining these drugs with Monoket causes increasing blood pressure. It is necessary to warn your cardiologist about taking other medicines to prevent negative effects of the therapy. Contact your doctor or pharmacist for more information about medicines’ interaction. Perhaps you will need some lab tests after examining your medical history.

You are not recommended to use Monoket if:

  1. You are a pregnant woman or plan pregnancy. Breastfeeding must be stopped until the end of the course.
  2. If you have already been taking pharmacy which negatively interacts with Monoket.
  3. If you have got an individual intolerance to this medication or allergic reactions on one of its ingredient.
  4. If there are other heart or blood problems except for angina (heart failure, heart attack, anemia).
  5. The article might not provide the whole list of contradictions. Consult the professional before starting the therapy.

Where to buy?

Monoket can be bought in the pharmacy or ordered online without prescription.