The most detailed information on Paxil CR: video and pictures

Paxil CR Uses

Paxil CR is used for treating of a depression, panic disorders and social alarming disorder (extreme pavor of interaction with others or to address others that disturbs normal life).

Paxil CR

Paxil CR

Brand(s): Paxil CR


Clinico-pharmacological group

Reception of a Paxil Cr has no adverse impact on quality and duration of a dream in the mornings. Besides, the dream can improve in process of implication of effect of treating by Paxil Cr. When using hypnagogues of short action in a combination with antidepressants additional side effects didn’t arise. In the first some weeks of therapy Paxil Cr effectively reduces symptoms of a depression and suicidal thoughts. Results of researches in which patients accepted Pxil Cr on an extent till 1 year, showed that the preparation effectively prevents recurrence of a depression. Controlled clinical trials of a Paxil Cr at treatment of a depression at children and teenagers (7–17 years) didn’t prove its efficiency therefore the preparation isn’t shown for treating of the specified age group. Paxil Cr is effective at treatment of the obsessivno-compulsive disorder (OCD) at adults, and also at children and teenagers at the age of 7–17 years. It’s established that at treating of panic disorder at adults a combination of a Paxil Cr and cognitive and behavioral therapy it’s significant more effectively, than one cognitive and behavioral therapy. Researches showed that Paxil Cr possesses insignificant ability to inhibit anti-hypertensive effects of a guanetidin.

Paxil CR

Paxil CR

Composition, structure and packing

The tablets covered with a film cover oval, biconvex, consist of paroxetine hydrochloride equivalent to 12.5 mg (yellow tablets), 25 mg (pink tablets) and 37.5 mg (blue tablets). The preparation available in bottles of 30

Basic ingredient:

paroxetine hydrochloride

Other ingredients:

colloidal silicon dioxide, glyceryl behenate, hydroxypropyl methylcellulose, lactose monohydrate and others

The composition of the coating film:

1 tablet of Paxil Cr contains: 12,5 mg, 25mg, 37,5 mg of a paroxetine as paroxetine hydrochloride. Preparation excipients: hydroxypropyl methylcellulose, lactose monohydrate, magnesium stearate


Paxil’s Cr tablet is drunk in the morning, not chewed. Use after food (though the food doesn’t influence Paxil’s Cr absorption), wash down with water. Disposable the daily dose is accepted. At therapy of a depression, the social phobia, post-traumatic stress disorder should use to the scheme: 20 mg daily in the first some weeks. At an inefficiency of this dose carry out weekly augmentation at 10 mg (for example, on the third week the daily dose will make 30 mg, on the fourth – 40 mg). The maximum rising of a dose of Paxil Cr to 50 mg/days. In a gerontology and at the impaired patients begin with a half-tablet (10 mg). For this purpose, the tablet is broken after risk, and the soulmate postponed in the blister pack until the following reception. At good tolerance of a dose and insufficient therapeutic effect it can be raised on 10 mg a week. Such patients can enlarge Paxil’s Cr dose to 40 mg.

The similar scheme of dosage is used also at a renal failure, existence of pathologies of a liver at patients. Treatment is long, its term is defined by the doctor. Obsessive-compulsive disorder is stopped by Paxil Cr according to the scheme which includes an initial dose 20 mg, with the subsequent augmentation at 10 mg weekly (in the absence of the expected therapeutic effect). The most admissible augmentation to 60 mg on reception. At panic attacks Paxil Cr prescribe in a dose 10 mg/days in an initiation of treatment. The minimum dose is used because of danger of an exacerbation of a symptomatology in an initiation of treatment. The dose can be enlarged (as much as possible to 60 mg/days). The augmentation is carried out gradually, weekly adding 10 mg to the main dose. Antirecurrent therapy consists in a maintenance dose 20 mg/days. The minimum course of treating of Paxil Cr for 4 months. At the end of a course for Paxil’s Cr cancellation the dose starts being lowered by 10 mg/week gradually. The doctor can prescribe other scheme of cancellation of a preparation if there are undesirable symptoms of a withdrawal.


Overdosage symptoms of Paxil Cr following: vomiting, nausea, asthenia or excessive exaltation, sleepiness, giddiness, cramps, ischuria, disturbances of a cardiac rhythm, syncopes, confusion of consciousness, lump, mydriasis, change of arterial pressure, maniacal reactions, aggression. Symptoms of a liver failure (an icterus, signs of a cirrhosis, hepatitis) can also develop. At joint reception of toxic doses of Paxil Cr with psychotropic drugs of ethanol can be cause loss of life

Side effects

At Paxil’s Cr reception can be observed:

  • nervousness,
  • emotional lability,
  • sleeplessness;
  • headaches,
  • migraines;
  • sleepiness,
  • asthenia;
  • tremor,
  • myoclonus, convulsive implications;
  • aggravation of a depression, depersonalisation;
  • the increased sweating;
  • dryness in a mouth;
  • anemic implications, limfoadenopatiya, leukopenia;
  • pressure decrease, orthostatic hypotension (in rare instances);
  • emergence of hematomas, bleedings;

Indications for use

The main indication is depressions of various genesis. Apply Paxil Cr at a situational, atypical, post-psychotic depression, a dysthymia. The preparation is effective at obsessional states (obsessivno-compulsive disorders), panic attacks, social phobias, agoraphobias, alarming disorders of various genesis, nightmares. Тhe preparation is effective at antirecurrent therapy alarming-phobia states. Positive results take of therapy by Paxil Cr at patients are observed, treatment by which standard antidepressants was unsatisfactory. Paxil’s Cr reception at patients with post-traumatic stress disorder. Paxil Cr is possible to apply long, and with the preventive purpose also.


Paxil’s reception is contraindicative:

to patients till 18 years;

in the period of a lactemia;

to the patients receiving treating by MAO inhibitors, pimozidum, tryptophan, thioridazinum;

at a hypersensitivity to a paroxetine, preparation excipients.

Where to buy?

You can get the preparation in pharmacy