Sinequan: Indications, Side Effects, Warnings, Drug Information, Description, User

Sinequan Indications

Sinequan treats depressive disorders and helps people to struggle with alcoholism. This medicament was developed by American pharmaceutical company Pfizer Inc. The main component of this drug elevates serotonin in person’s brain. It helps to improve patient’s mood. Sinequan has been clinically tested. It is not recommended to take this medicine without prescription of your doctor.

Sinequan Indications

Sinequan Indications

Brand(s): Sinequan.

Manufacturer(s): Pfizer Inc., USA.

Clinico-pharmacological group: Sinequan is the medicament which helps in treatment of depression. The drug is a part of tricyclic antidepressants. This group of drugs can improve person’s mood by means of elevating of serotonin and noradrenaline in patient’s brain.

Composition, structure and packing: Sinequan is the drug which comes in pink-white capsules. Each capsule includes 50 milligram of active components of the medicament.

Basic ingredient: Sinequan includes doxepin – the main ingredient of this medicament. This component helps to elevate the level of serotonin and noradrenaline in patient’s brain. It helps to struggle with depression by means of improving patient’s mood.

Other ingredients: Sinequan includes next other components:

  • Glycerin;
  • Sodium hydroxide;
  • Methylparaben;
  • Propylparaben;
  • Water;
  • Hydrochloric acid;
  • Peppermint flavor.

The composition of the coating film: Capsule shell comprises of sodium lauryl sulfate, gelatin, magnesium stearate and starch.


Your proper dosage can be determined only by your specialist. Do not self-medicate. This drug is taken by mouth. Take it during or after meal. It will help to avoid mucous membrane irritation of stomach. Take this medicine 1-2 times a day. In case of moderate depression – it is recommended to take 75 milligrams a day. Then dosage can be changed. Average dosage amount is 75-150 milligram a day. In case of expressive depression – take 300 milligrams a day. One intake should not be more than 150 milligrams. If you have problems with sleep – it is better to take the biggest part of dosage before going to bed. As usual, duration of treatment is 2-3 weeks. Discontinuation of drug should be gradual – decrease dosage of Sinequan gradually. Do not stop taking the drug without doctor’s instructions. Always follow his or her prescription.


Overdose can be consequence of self-medication and violation of doctor’s instruction. Take Sinequan only under the care of your specialist. It will reduce the risk of side effects. After-effects of overdose are: faint, chest pain, swimming of the head and irregular heartbeat. If you feel that you have taken more than you need – see your doctor.

Side effects

Side effects can be caused by overdose and self-medication. Do not take this medicament without prescription of your doctor. Possible after-effects are blurring of vision, corectasia, tachycardia, dry mouth, acute organic brain syndrome, uncleared bowels, ileus paralytic, drowse, anxiety, asthenia, disorientation, nervousness, mania, aggression, memory impairment, depersonalization, insomnia, anxiety dreams, swimming of the head, headache, peripheric neuropathy, extrapyramidal syndrome, epilepsy spells, vomiting, nausea, epigastric burning, appetite and weight loss, aphtous stomatitis, flavor reversion, diarrhea, tachycardia and arrhythmia. If you have any mentioned symptoms – immediately visit your doctor. Otherwise, you can face with complications of disease. Be careful and follow medical instructions. It will help you reduce the risk of side effects.

Indications for use

Sinequan is used for treatment major depressive disorders, depression, anxiety, premenstrual syndrome, peptic ulcer, nervousness and alcoholism. This drug is available on prescription of your doctor. Therefore, do not take this medicament without instruction of your specialist who can determine your diagnosis, proper dosage and duration of treatment for the avoidance of overdose and complications of disease.

Contra indications

Forget about taking this medicine in case of allergy to any ingredient of the drug. Other reasons to refrain from using this medicament are: myocardial infarction, acute alcohol intoxication, acute hypnotic intoxication and breastfeeding. Children who are younger than 12 years old – should refrain from taking Sinequan too. Do not mix intakes of Sinequan and monoaminooxidase inhibitor and do not take it at the same time. Be careful and attentive in case of chronic alcoholism, pregnancy, cardiovascular disease, blood-stroke, liver and kidney failure and confusional insanity. In order to avoid complications and side effects – follow doctor’s prescription and if your specialist does not prescribe Sinequan – do not use it and do not self-medicate.

Where to buy?

Sinequan is a good drug for treatment of disorders, depression, anxiety and alcoholism. It was developed by famous American pharmaceutical company Pfizer Inc. This medicament is widespread all over the world. Therefore, you can find it at pharmacy. If your pharmacy has no this medicament on the marker, you can make an order online.