Clinico-pharmacological group of Neurontin
Release form, composition and packing
Capsules are white, with a blue inscription “Neurontin 100 mg” and “PD”; contents of capsules – a white or almost white powder.
Active substance of Neurontin
Gabapentin 100mg, 300mg, 400mg, 600mg, 800mg
Excipients: poloxamer 407, copovidone, corn starch, magnesium stearate, “Opadry” white (Opadry White), talc, giproloza, polishing wax.
Neurontin – a description of the preparation, application instructions, reviews. Neurontin oral tablets (Neurontin). Instruction for medical use of the drug.
Indications for use of Neurontin
– The treatment of neuropathic pain in adults aged 18 years and older;
– Monotherapy of partial seizures with secondary generalization and without adults and children over the age of 12 years;
– As an additional tool in the treatment of partial seizures with secondary generalization and without adults and children aged 3 years and older.
Contraindications of Neurontin
– Children under 3 years of age;
– Hypersensitivity to gabapentin and other ingredients.
With care, use in patients with renal insufficiency.
Dosage and administration of Neurontin
Inside, regardless of meals or with food.
Epilepsy. Adults and children over 12 years: the effective dose – 900-3600 mg / day.
Children 3-12 years: effective dose – 25-35 mg / kg / day in 3 equal doses.
Neuropathic pain in adults. The initial dose is 900 mg / day in 3 divided doses equal doses; if necessary, depending on the effect of gradually increasing the dose until a maximum of 3600 mg / day. Initiate therapy on the selection of doses should be as described in the first table.
Overdose of Neurontin
Symptoms: dizziness, double vision, impaired speech, drowsiness, lethargy, diarrhea. Treatment: gastric lavage, reception activated carbon, symptomatic therapy. Patients with severe renal insufficiency, hemodialysis may be indicated.
Side effects of Neurontin
In the treatment of neuropathic pain Body as a Whole: accidental injury, asthenia, back pain, flu syndrome, headache, infection, pain of various localization, peripheral edema, weight gain; Digestive tract: constipation, diarrhea, dry mouth, dyspepsia, flatulence, nausea, vomiting, abdominal pain; Nervous System: gait disturbance, amnesia, ataxia, confusion, dizziness, hypesthesia, somnolence, abnormal thinking, tremor;
Respiratory: shortness of breath, sore throat;
Skin and subcutaneous tissue: skin rash;
Special Senses: amblyopia.
In the treatment of partial seizures
Body as a whole: back pain, fatigue, fever, headache, viral infection, peripheral edema, weight gain, fatigue, malaise, swelling of the face;
Cardiovascular system: symptoms of vasodilation or hypertension;
Digestive tract: constipation, dental disease, diarrhea, dyspepsia, increased appetite, dry mouth or throat, nausea and / or vomiting, abdominal pain, flatulence, anorexia, gingivitis;
blood system, lymphatic system: leukopenia, purpura (often described as her bruises, occurred when a physical injury);
Musculoskeletal system: fractures, myalgia, arthralgia;
Nervous system: amnesia, ataxia, confusion, incoordination, depression, dysarthria, emotional lability, insomnia, nervousness, nystagmus, drowsiness, abnormal thinking, tremor, muscle twitching, dizziness, hyperkinesia; strengthening, weakening or absence of reflexes, paresthesia, anxiety, hostility;
Respiratory system: cough, pharyngitis, rhinitis, pneumonia;
Skin and subcutaneous tissue: abrasions, acne, skin itching, skin rash;
Special Senses: amblyopia, diplopia, blurred vision;
Urogenital: urinary tract infection, impotence.