Cleocin: semisynthetic antibiotic

Cleocin: semisynthetic antibiotic

Cleocin is semisynthetic antibiotic and treats bacterial infections caused by microorganisms. The major component of this medicament is Clindamycin. It belongs to lincosamides group. Cleocin is taken by mouth and can be used for treatment of children. This medicament is manufactured by Pfizer’s subsidiary American pharmaceutical company Pharmacia and Upjohn Company. This company is popularly known as manufacturer of high-quality medical products. Cleocin is potent antibiotic, therefore, it is available only on doctor’s prescription. Before taking this medicine a patient should get acquainted with the list of possible side effects. Taking this drug, a person should be careful and follow prescription of specialist.



Brand(s): Cleocin.

Manufacturer(s): Pharmacia and Upjohn Company (a subsidiary of Pfizer), USA.

Clinico-pharmacological group: Cleocin is semisynthetic antibiotic, which belongs to lincosamides group, which is formed from lincomycin.

Composition, structure and packing: This medicament comes in blue capsules. Capsules’ size is 2 cm 2 mm. One capsule includes 300 milligram of active ingredient.

Basic ingredient: Clindamycin is a major component of this medicament. This ingredient is a part of lincosamides group, which is formed from lincomycin. This active component takes antibacterial effect.

Other ingredients: Also Cleocin includes the next components:

  • Corn starch;
  • Magnesium stearate;
  • Lactose.

The composition of the coating film: Capsule shell of this medicament comprises of gelatin, talc and titanium dioxide.


Dosage amount is patient-specific and determined only by doctor. This medicament is taken by mouth. As usual, adults should take 150 – 450 milligram every 6 – 8 hours. Children should take 8 – 25 milligram / kg a day divided in 3-4 intakes. In order to reduce the risk of gastric irritation, it should be taken with glass of water. Duration of treatment is determined by specialist. Before taking this drug you should get acquainted with the list of possible side effects. Always be careful and do not take more than you need. Do not stop taking the medicine without doctor’s instructions.


Symptoms caused by overdose: appearance and increasing of side effects. Constant diarrhea, and vomiting are also symptoms of overdose. If you face with overdose or side effects, you should immediately visit your specialist.

Side effects

This drug is available only on specialist’s prescription. Thus, a patient should follow special instructions and should not violate a rule of intake of this medicament. Possible side effects of Cleocin: disorder of neuromuscular pathway, leukopenia, eosinophilia, agranulocytic angina, collapse, hypotension, abdominal pain, pseudomembranous colitis, esophagitis, nausea, vomiting, diarrhea, disbacteriosis, jaundice, hyperbilirubinemia, metallic aftertaste, maculopapular rash, urticaria, itching, dermatitis, erythema multiforme, toxic epidermal necrolysis, anaphylactoid reactions, azotemia, oliguria, proteinuria, arthritis, development of superinfection. If you have any mentioned symptoms – visit your doctor.

Indications for use

Cleocin is prescribed for treatment of bacterial infections caused by microorganisms. It treats diseases such as pharyngitis, tonsillitis, sinusitis, otitis media, bronchitis, pneumonia, lung abscess, empyema, fibrosing alveolitis, osteomyelitis, septic arthritis, acne, boils, cellulitis, impetigo, whitlow, infected wounds, abscesses, erysipelas, septicemia, peritonitis, abscesses of the abdominal cavity, endometritis, adnexitis, abscess of the fallopian tubes, salpingitis, pelvioperitonit, periodontal abscess, tropical malaria, scarlet fever, diphtheria. This medicament is available only on doctor’s prescription.

Contra indications

It is a good practice to refrain from taking this medicine in case of allergy to any component of this drug. Also it is not recommended to begin taking this medicament if a patient has ulcerative colitis. Do not use this medicine during pregnancy and breastfeeding. If a person has any suspicions that he or she has contra indications, it is better to consult with specialist.

Antibacterial drugs deteriorate the normal intestinal flora. It can contribute to enhanced proliferation of clostridia. Therefore, a patient should be careful and follow all doctor’s recommendations.

Where to buy?

Cleocin is produced by Pfizer’s subsidiary Pharmacia and Upjohn Company. Therefore, this medicament is widespread around the world. It is possible to find this drug at any pharmacy. However, if it is absent, a person can make an order online. Also a patient can ask his or her specialist where he or she can buy this drug.