Ampicillin: for treating infections which are caused by bacteria

Ampicillin antibiotic

Ampicillin is an antibiotic which is used for treating infections which are caused by bacteria. It is directed to treat infections of the respiratory, urinary tract, meningitis, and sinusitis. Ampicillin is declared by the World Health Organization to be one of the most necessary medications.

Ampicillin antibiotic

Ampicillin antibiotic

Brand(s): Ampicillin, Principen

Manufacturer: Mylan Institutional LLC

Clinico-pharmacological group:

Aminopenicillin antibiotic

Composition, structure and packing:

Blue/grey capsules

Basic ingredient:

Ampicillin, 250-500 mg

Other ingredients:

Black iron oxide, lactose monohydrate, and titanium dioxide.

The composition of the coating film:

Gelatin, FD&C Blue #1, FD&C Red #3, FD&C Red #40, silica gel

Basic ingredient:



Do not start taking medications without consulting the doctor first. Ampicillin is a serious medicine which is not used for treating problems caused by virus such as cold, flu, etc. Using the antibiotic without the instruction given by specialist may lead to negative body reactions, allergy or worsening of the patient’s condition. The dosage given below is not an instruction to follow and is about using Ampicillin containing in the capsules.

The usual dose for adults is 250-500 mg four times a day. If necessary, the dose may be increased to 3 g per day.

Name of infections Dosage

For adult patients

Infections of gastrointestinal and urinary tract 500 mg 4 times daily

Listeria 50 mg/kg 6 times a day

Meningitis 14 g per day

Gonococcal urethritis 3,5 g once

Mild gonorrheal urethritis 500 mg once

Infections of respiratory system 250-500 mg 4 times per day

The dose for pediatric patients is ranging 25-50 mg/kg 4 times daily. The dosage for children weighing more than 20 kg is the same as the adult dosage.

The doctor might change the dose during the treatment according to your indications and general state. Each patient may have an individual dose or a regimen if he or she has hypersensitivity to Ampicillin or other antibiotics. Follow the instructions sold with the medicine and the doctor’s schedule in order to reach the best results, and to avoid worsening of the state. It is necessary to continue the medication for the whole term even if you think your state is improving. The therapy may last 7-14 days.


The therapy must be discontinued, should you suspect taking too many capsules. The patients with overdose are usually prescribed with a supportive treatment. The symptoms of the overdose may include problems with gastrointestinal tract, or their worsening; signs of allergy.

Side effects

As in the most cases, the appearing of the side effects is closely connected with the hypersensitivity to penicillin and other groups of antibiotics. They are likely to occur if the patient has previously experienced allergic reactions, or its medical history includes severe deceases such as asthma. The reported signs of the side effects were:

  • Vomiting
  • Nausea
  • Rush (during the experiment it was found that it could cover the whole body including palms, oral mucosa. Such severe symptom successfully disappeared in two-tree days after the treatment.)
  • Anaphylaxis (one more the severest form which is a result of hypersensitivity)

The milder symptoms of the overdose are

  • Fatigue
  • Tiredness or muscles weakness
  • Headaches
  • Loss of appetite

Some of the allergic reactions, including rush may mean that the therapy should be stopped. In some cases, it may be decided by the specialists to continue the therapy combining Ampicillin with antihistamines.

Indications for use

Ampicillin is prescribed to treat bacterial infections and has the antibacterial effect. It is usually administrated for the treatment of respiratory, urinary tract, infections of throat, nose, and ears. It also may be directed in cases not listed in this article. As other antibiotics, Ampicillin is not for treating viral infections and must be taken carefully under the doctor’s supervision.


Ampicillin is contraindicated to the patients with hypersensitivity to penicillin. There were reported serious and fatal reactions caused by the severe allergy. Anaphylaxis is one of them. You may not be able to take the antibiotic if you have got liver or kidney failure.

Warn your physician if you are allergic to any medicines, chemical liquids, eating products, etc. Ampicillin is not prescribed to pregnant women as it may harm the fetus. Ampicillin passes into the breastmilk, so tell your doctor if you are breastfeeding. The antibiotic is not prescribed to children less than 1 month.

Where to buy?

Buy Ampicillin in pharmacies using the prescription. The cost for the antibiotic is between 0.13 and 1. 20 USD. Ordering without prescription is possible in online pharmacies. Some of them offer delivering to your home or the place of work.