Ibuprofen: anti-inflammatory medicine

Ibuprofen: anti-inflammatory medicine

Ibuprofen is a nonsteroidal anti-inflammatory medicine, whose work is about decreasing inflammation, and pain syndrome. It is administrated for treating complaints caused by head-, tooth-, and backaches, arthritis, injuries, etc.



Brand(s): Ibuprofen, Advil, Genpril, Midol IB, Motrin IB, Proprinal

Manufacturer: Amneal Pharmaceuticals, Pfizer, Cipla

Clinico-pharmacological group:


Composition, structure and packing:

Tablets, oval, 800 mg, imprinted ‚ÄúIP 466‚ÄĚ, white, 19 mm

Basic ingredient:

800 mg Ibuprofen

Other ingredients:

Talc, sodium, octadecanoic acid, microcrystalline cellulose, polyviol, titanium white.

Basic ingredient:



Problem Dosage

For patients older than 12 y.o.



Psoriatic arthritis

Ankylosing spondylitis

400- 600 mg 3-4 times daily

1. Rheumatoid arthritis 800 mg 3 times daily

Strained muscles, injuries 1600 – 2400 mg once a day

Mild pain 1200 mg per day

Fever 200-400 mg every 4-6 hours

For children aged 6 months-12 y.o. the dosage is measured 5 mg/kg. Ibuprofen may cause some risks if it is not used properly; especially it increases the risk of heart attack. Do not start taking Ibuprofen without consulting the specialist first. The doctor will make sure whether you are able to use the medication or not. The dosage should be measured according to the indications and the general state of the patient. Following doctor’s instructions is necessary for achieving positive results. Do not stop the therapy unless you are recommended to discontinue your treatment, even if your symptoms are improving.


Get an emergency medical help if you suspect overdose. Taken for too long time, Ibuprofen is likely to cause liver damage, as well as the overdose does the same. There were reports that the medicine led to the permanent liver damage due to the doubled length of treatment. The common signs of overdose are:

  • Dizziness
  • Headache
  • Vomiting
  • Nausea
  • Diarrhea
  • Sickness

Side effects

There were reported that among examined patients, different adverse reactions appeared among those, where the dose was increased to 3000 mg daily.

Patients who have severe gastrointestinal problems run a risk of having the following side effects:

  • Vomiting
  • Nausea
  • Diarrhea
  • Dyspepsia

Patients who have liver problems are strongly recommended to monitor the liver function tests. In rare cases ductopenia (or the number of deceases that lead to hepatic bile ducts) may occur.

Hyponatremia is an adverse effect referred to the metabolic side effects, also appeared because of the overdose. There were mentioned about the possibility of occurring such reactions as skin rush, dermatitis which can be fatal.

Seek for medical help if you experience signs of allergic reactions such as:

  • Swollen face
  • Hard breathing
  • Rush, urticarial
  • Blurred vision

Indications for use

Ibuprofen is indicated to treat such deceases as osteoarthrosis, algodismenorrhea, psoriatic arthritis, ankylosing spondylitis, rheumatoid arthritis, pain syndrome, inflammation. It may also be indicated for other purposes, not given in the article.


Firstly, it must be noted that even people without heart problems are at the risk of acute myocardial infarction or an attack of angina. Ibuprofen must not be used before or after the heart surgery. Ibuprofen is not directed to the patients with a known allergy to it. It is necessary to find out whether the patient has ever had the allergic reactions for the eating products, chemical liquids, drugs such as aspirin, etc. Some inactive ingredients also may cause allergy. You are not able to take the medicine if you suffer from asthma.

Alcohol use disorder, as well as the gastrointestinal problems increases the risks of the adverse effects during the treatment. Such patient should be treated under the cautious supervision. Ibuprofen may be contraindicated to those who have kidney or liver failure. In case, the medication is prescribed to them, the monitoring lab tests are necessary during and, sometimes, after the treatment. Such cases as

  • Diabetes
  • Hypertonia
  • Bleeding disorders
  • Anemia

must be taken into account. The dosage must be carefully measured by the specialist not to do harm. It is strongly not recommended for pregnant women to use Ibuprofen in the last 3 months of pregnancy. It is still incompletely known whether using Ibuprofen earlier is safe, so warn the doctor whether you are pregnant or plan pregnancy. It is unknown if the medicine passes into the breast milk or if it does any harm to newborns.

Giving Ibuprofen to children under 2 y.o is not recommended without the doctor’s advice. Do not consume alcohol during the treatment. Taking aspirin should be stopped while you take Ibuprofen.

Where to buy?

Buy Ibuprofen in the pharmacy using the prescription. An average price for Ibuprofen ranges from 17 to 22 USD.