Flonase nasal : Uses, Side Effects, Interactions, Where buy?

Active Ingredient: Fluticasone

Pharmachologic effect

Flonase – is a means for local use in the nasal cavity. When applied topically, Flonase reduces the product of proinflammatory mediators, as well as biologically active agents (including leukotrienes, prostaglandins, cytokines and histamine).

Flonase nasal

Flonase nasal

It has a pronounced anti-allergic, anti- edematous and anti-inflammatory effect. Inhibits the proliferation of lymphocytes, eosinophils, macrophages, mast cells, neutrophils. It joins to a glucocorticoid hormone receptors, causing a powerful anti-inflammatory effect- thanks to this effect of the drug, develops immediately (within 2-4 hours after intranasal administration). Impact on both the early and late stage of the allergic process.

Reduces the severity and relieves the main features of allergic reactions in the nose: rhinorrhea, sneezing, nasal discomfort, a feeling of pressure in the sinuses, itchy nose, nasal congestion, discomfort in the eye and other ocular symptoms of allergic rhinitis.


For the treatment or preventative therapy for year-round or seasonal allergic rhinitis.

Mode of application:

The drug is intended solely for the use of intranasally. It is regularly used in the mode prescribed by your doctor to achieve the maximum therapeutic effect. It is desirable to introduce Flonase in the morning. The adult dose – 2 doses (100 micrograms) in each half of the nose 1 per day – is used for children older than 12 years. The total daily dose- 200 micrograms.

A short time, you can use the drug 2 times a day for 2 doses (100 mcg) for quick relief of symptoms of allergic rhinitis, and then the dosage is reduced to the recommended. After 3-4 days of application developing the maximum therapeutic effect.

The maximum permissible dose of Flonase a day – 4 doses in each half of the nose (400 micrograms).

For elderly patients to change the dosage of the drug is not needed. In pediatrics used the drug from 4 years – 1 dose (50 mcg) in each half of the nose one time per day. The maximum permitted daily dose of the drug for children – 2 doses in each half of the nose (200 micrograms).

Side effects:

Local reactions, such as:

  • dryness and irritation of the nasopharynx;
  • taste and odor;
  • nasal bleeding;
  • burning sensation;
  • stuffy nose;

Rare – perforation of the nasal septum (especially in surgical interventions in the nasal cavity in history).

Allergic reactions:

  • possible skin rash;
  • swelling of face and tongue;

Rare – anaphylactic reactions and bronchospasm.

Other: headache.


  • In pediatric practice – children up to 4 years;
  • Allergic reactions to the active substance or any other drug of its constituent ingredients.


When pregnancy it is not recommended to prescribe the Flonase. If the drug is required for use in this group of women, before it appointment, evaluate the ratio of the potential risk to the child and the anticipated benefits to the mother.


It is not registered signs of chronic and acute overdose of Flonase.

The form of issue:

Spray for intranasal use in dark glass bottles of 60 or 120 doses. Spray as an opaque white slurry do not contains impurities. The vial is provided with adapter and metering device. The bottle is packed in a cardboard box.

Storage conditions:

At a temperature of 30 degrees Celsius. Shelf life – is 2 years. Prescription is from the pharmacies.

Special instructions

Be careful when transferring patients from systemic corticosteroid therapy to treatment with Flonase if there is reason to impaired function of the adrenal glands.

With prolonged use of the drug requires regular monitoring of adrenocortical function.

Patients should be warned that if after 7 days of continuous use of the drug the improvements does not occur, you should seek medical advice.

With continued use of the drug for more than 6 months requires the medical supervision of the patient.

In most cases, the use of Flonase can successfully control the symptoms of seasonal allergic rhinitis, but in some cases, at a very high concentration of allergens in the air in the summer, you may need additional therapy.

For relief of ocular symptoms on a background of successful treatment of seasonal allergic rhinitis may require additional treatment.

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