Drug Information: Indications, Side Effects, Warnings
Category: Â Anti-inflammatories, Arthritis, Analgesics
The preparation is used to treat diseases such as:
rheumatoid, psoriatic, juvenile chronic arthritis, Paget’s disease and Reiter, neuralgic amyotrophy (disease Personeydzha-Turner), ankylosing spondylitis (ankylosing spondylitis), gouty arthritis, rheumatism. Pain: headache (including with menstrual syndrome), and toothache, lumbago, sciatica, neuralgia, myalgia, after injuries and surgical interventions, accompanied by inflammation, bursitis and tendonitis (the most effective in the localization of the shoulder and forearm). Algomenorrhea to save the pregnancy syndrome Barter (secondary hyperaldosteronism), pericarditis (symptomatic treatment), childbirth (as analgesic and tocolytic agent for premature birth), inflammatory processes in the pelvis, including adnexitis, cleft arterial duct. Infectious-inflammatory diseases of ENT organs with marked pain syndrome (in the complex therapy): pharyngitis, tonsillitis, otitis media. Feverish syndrome (including with chlamydia, other lymphomas and hepatic metastases of tumors sĂłlidnyh) – in case of failure of aspirin and paracetamol.
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Systemic side effects
From the nervous system and sensory organs: headache, dizziness, vertigo, agitation, irritability, excessive fatigue, sleepiness, depression, peripheral neuropathy, taste disturbance, hearing loss, tinnitus, diplopia, blurred vision, corneal opacity, conjunctivitis.
Cardio-vascular system and blood (blood, hemostasis): development (widening) of congestive heart failure, tachyarrhythmia, edematous syndrome, increased blood pressure, bleeding (from the gastrointestinal tract, gingival, uterine, hemorrhoids), anemia (including autoimmune hemolytic and aplastic), leukopenia, thrombocytopenia, eosinophilia, agranulocytosis, thrombocytopenic purpura.
From the digestive tract: NSAID-gastropathy, nausea, vomiting, abdominal pain, heartburn, loss of appetite, diarrhea, abnormal liver function (increase in liver transaminases, hyperbilirubinemia); With prolonged use at high doses – erosive and ulcerative lesions of the gastrointestinal tract.
With the genitourinary system: renal failure, proteinuria, hematuria, interstitial nephritis, nephrotic syndrome, papillary necrosis.
Allergic reactions: itching, rash, urticaria, exfoliative dermatitis, erythema nodosum, anaphylactic shock, bronchospasm, angioedema, toxic epidermal necrolysis (Lyell’s syndrome).
Other: hyperglycemia, glycosuria, hyperkalemia, photosensitivity; aseptic meningitis (usually in patients with autoimmune diseases), increased sweating; local reactions at the rectal: burning, itching, heaviness in the anorectal area, worsening of hemorrhoids.
If you have one or more symptoms, you should consult a doctor immediately.
Symptoms: nausea, vomiting, severe headache, dizziness, memory impairment, disorientation; in severe cases – paresthesia, numbness and cramps.
Treatment: symptomatic therapy. Hemodialysis is ineffective.
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