Ponstel: instructions of use

Active ingredient: mefenamic acid. Mefenamic acid is a non-steroidal anti-inflammatory agent. Substance Inhibits inflammation, inhibits the formation of inflammation, and the release from the depot tissue inflammatory mediators (serotonin, histamine, kinins, prostaglandins, and others.).

The nosological classification (ICD-10) of Ponstel

I00-I02 Acute rheumatic fever

I40 Acute myocarditis

J11 Influenza, virus not identified

K05.2 Acute periodontitis

M06.9 Rheumatoid arthritis, unspecified

M25.5 Pain in the joints

M45 Ankylosing spondylitis

M79.1 Myalgia

M79.2 Neuralgia and neuritis, unspecified

N94.3 syndrome premenstrual tension

Unspecified N94.6 Dysmenorrhea

R50 Fever of unknown origin

R51 Headache

R52.2 Other constant pain



Indications for use

Acute rheumatic fever, nonspecific (rheumatoid) arthritis, ankylosing spondylitis, arthralgia, myalgia, neuralgia, headache, toothache, fever, an infectious-allergic myocarditis, dysmenorrhea, premenstrual syndrome, colds and febrile diseases, influenza, periodontal disease (locally in the form).

Contraindications of Ponstel

Hypersensitivity, gastric ulcer and duodenal ulcer disease, inflammatory gastrointestinal diseases, kidney disease, and hematopoiesis.

Side effects of Ponstel

Nausea, heartburn, diarrhea, abdominal pain, anorexia, flatulence, gastrointestinal bleeding, constipation, weakness, drowsiness, nervousness, insomnia, blurred vision, albuminuria, allergic reactions (pruritus, facial swelling, rash).

With long-term use (12 months or more) – hemolytic anemia, decrease in hematocrit, violation of hematopoiesis. When blood levels of 100-200 mg / l and higher – muscle twitching, convulsions, vomiting.

Interaction of Ponstel

Salicylates and metamizole sodium enhance the anti-inflammatory effect. Thiamine, pyridoxine, barbiturates, phenothiazines, narcotic analgesics, caffeine, phenacetin, diphenhydramine potentiate analgesia.