Active ingredient: mefenamic acid. Mefenamic acid is a non-steroidal anti-inflammatory agent. Substance Inhibits inflammation, inhibits the formation of inflammation, and the release from the depot tissue inflammatory mediators (serotonin, histamine, kinins, prostaglandins, and others.).
The nosological classification (ICD-10) of Ponstel
I00-I02 Acute rheumatic fever
I40 Acute myocarditis
J11 Influenza, virus not identified
K05.2 Acute periodontitis
M06.9 Rheumatoid arthritis, unspecified
M25.5 Pain in the joints
M45 Ankylosing spondylitis
M79.2 Neuralgia and neuritis, unspecified
N94.3 syndrome premenstrual tension
Unspecified N94.6 Dysmenorrhea
R50 Fever of unknown origin
R52.2 Other constant pain
Indications for use
Acute rheumatic fever, nonspecific (rheumatoid) arthritis, ankylosing spondylitis, arthralgia, myalgia, neuralgia, headache, toothache, fever, an infectious-allergic myocarditis, dysmenorrhea, premenstrual syndrome, colds and febrile diseases, influenza, periodontal disease (locally in the form).
Contraindications of Ponstel
Hypersensitivity, gastric ulcer and duodenal ulcer disease, inflammatory gastrointestinal diseases, kidney disease, and hematopoiesis.
Side effects of Ponstel
Nausea, heartburn, diarrhea, abdominal pain, anorexia, flatulence, gastrointestinal bleeding, constipation, weakness, drowsiness, nervousness, insomnia, blurred vision, albuminuria, allergic reactions (pruritus, facial swelling, rash).
With long-term use (12 months or more) – hemolytic anemia, decrease in hematocrit, violation of hematopoiesis. When blood levels of 100-200 mg / l and higher – muscle twitching, convulsions, vomiting.
Interaction of Ponstel
Salicylates and metamizole sodium enhance the anti-inflammatory effect. Thiamine, pyridoxine, barbiturates, phenothiazines, narcotic analgesics, caffeine, phenacetin, diphenhydramine potentiate analgesia.