Reminyl is used to treat dementia caused by Alzheimer’r disease.
Funds for the treatment of dementia, a cholinesterase inhibitor.
The nosological classification (ICD-10)
F00 Dementia in Alzheimer’s disease
Active substance of Reminyl
galanthamine hydrobromide (calculated as base) is 8 mg
Other ingredients: sugar spheres (consisting of sucrose and corn starch); hypromellose 2910 (5 mPa.s); macrogol 400; ethyl cellulose (20 mPa.s); diethyl phthalate
Capsule shell: Gelatin; titanium dioxide; red iron oxide (16 and capsule 24 mg); yellow iron oxide (24 mg capsules)
Indications for use Reminyl
dementia of the Alzheimer type mild to moderate, including c chronic disorders of cerebral circulation.
Contraindications of Reminyl
hypersensitivity to galantamine hydrobromide or to any excipient, which is a part of this drug;
patients with severe renal impairment (Cl creatinine less than 9 ml / min) – due to a lack of data on the application;
severe liver dysfunction.
Precautions: General anesthesia; asthma, COPD; bradycardia, AV block, sick sinus syndrome, unstable angina; concomitant therapy drugs, inhibiting the heart rate (digoxin, beta-blockers); gastric ulcer and duodenal ulcers, gastrointestinal tract obstruction, the period after undergoing surgery on the digestive tract; epilepsy; obstruction of the urinary tract, the period after undergoing surgery on the bladder.
Side effects of Reminyl
Immune system: rarely – hypersensitivity.
Disorders of metabolism and nutrition: common – loss of appetite; infrequently – dehydration.
Mental disorders: often – depression, hallucinations; rarely – visual and auditory hallucinations.
From the nervous system: often – dizziness, headache, tremor, fainting, confusion, drowsiness; infrequently – dysgeusia, hypersomnia, paresthesia, convulsions. Seizures are a class-effect observed with the use of acetylcholinesterase inhibitors – for treatment of dementia and include seizures, and seizures.
Ophthalmic disorders: rarely – blurred vision.
On the part of the ear and labyrinth: rarely – ringing in the ears.
From the CCC: often – bradycardia, increase in blood pressure; infrequently – AV blockade degree I, palpitations, sinus bradycardia, supraventricular extrasystoles, flushing, reduction of blood pressure.
On the part of the digestive tract: often – nausea, vomiting; often – diarrhea, abdominal pain, dyspepsia, gastrointestinal discomfort; infrequently – retching.
Hepatobiliary disorders: rare – hepatitis.
With the skin side and subcutaneous tissue disorders: rarely – increased sweating; very rarely – Stevens-Johnson syndrome, acute generalized eczematous pustulosis, erythema multiforme.
On the part of the musculoskeletal system and connective tissue disorders: often – muscle cramps; rarely – muscle weakness.
General disorders: often – fatigue, weakness, malaise.
Changes in measuring and laboratory parameters: often – weight loss; rare – increase in liver enzymes.
Injury, poisoning and complications of manipulation: often – drop lacerations.
Dosage of Reminyl
Inside, 1 time a day (in the morning), preferably during meals.
The initial dose. The recommended starting dose is 8 mg / day.