Desogen (Desogestrel-ethinyl Estradiol)

Drug Information: Indications, Side Effects, Warnings

Category: Women’s Health, Birth Control

Generic Desogen is used for preventing pregnancy.

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Brand(s): Novelon

Manufacturer: Organon

Pharmacological action. Contraceptive product. Inhibits the secretion of pituitary gonadotropins. The contraceptive effect is due to the influence on the hypothalamic-pituitary-ovarian system.

Indications for use: Contraception


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Hypersensitivity, venous or arterial thrombosis / thromboembolism (including deep vein thrombosis shin, pulmonary embolism, myocardial infarction, stroke) including a history of thrombosis precursors (including transient ischemic attack, angina), including a history of migraine with focal neurological symptoms history, diabetes with vascular lesions, the presence of severe or multiple risk factors for venous or arterial thrombosis (including severe hypertension with BP 160/100 mm Hg or more) pancreatitis (including history), accompanied by severe hypertriglyceridemia, severe liver disease (up to normalization of function of the liver), including a history of liver tumors, including a history of hormone-dependent malignancies genitals and mammary glands (including suspects), vaginal bleeding of unknown etiology, smoking women older than 35 years (more than 15 cigarettes per day), pregnancy (including estimated), lactation .


Precautions: Conditions that increase the risk of venous or arterial thrombosis / embolism: age older than 35 years, smoking, family history, obesity (body mass index over 30 kg / m), dislipoproteinemia, hypertension, migraine, valvular heart disease, atrial fibrillation, prolonged immobilization, major surgery, surgery on the lower extremities, severe trauma, varicose veins and superficial thrombophlebitis, postpartum, changes in biochemical parameters (activated protein C resistance, hyperhomocysteinemia, antithrombin deficiency III, protein C deficiency, or S, antiphospholipid antibodies, including antibodies to cardiolipin, lupus anticoagulant). Diabetes, lupus, hemolytic uremic syndrome, Crohn’s disease, ulcerative colitis, sickle-cell anemia; hypertriglyceridemia (including family history), acute and chronic liver disease, including congenital hyperbilirubinemia (Gilbert syndrome, Dubin-Johnson syndrome, Rotor) to restore the biochemical parameters.


Dosing: Inside, squeezed liquid, 1 tablet a day (starting no later than 5 days cycle 1 day cycle — 1 day of menstruation) daily, at one and the same time, without interruption, for 21 days, then take a break 7 days. During the first 14 days is necessary to use additional contraceptive measures.


Side effect: Thrombosis or thromboembolism (including myocardial infarction, stroke, deep vein thrombosis, pulmonary embolism). Chloasma (especially if there is a history of chloasma during pregnancy), Crohn’s disease, ulcerative colitis, intermenstrual bleeding (spotting or heavy) in the first few months of taking the drug, and allergic reactions.

Perhaps: thromboembolism hepatic, mesenteric, renal, retinal arteries and veins; headache, migraine, changes in libido, emotional lability, depression; dysfunction of the gastrointestinal tract, including nausea, vomiting; tenderness, enlargement and breast engorgement, galactorrhea; weight gain, fluid retention, increased blood pressure; skin rash, erythema nodosum, or exudative, intolerance to contact lenses, a change in vaginal secretions; emergence or worsening jaundice and / or pruritus associated with cholestasis, cholelithiasis, porphyria, lupus, hemolytic uremic syndrome, chorea, gestational herpes, hearing loss due to otosclerosis.



Symptoms: nausea, vomiting, girls — bleeding from the vagina.

Treatment: symptomatic.

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