Drug Information: Indications, Side Effects, Warnings
Category:Â Respiratory Tract,Â Asthma
Generic Advair is used for long-term treatment of asthma and chronic obstructive pulmonary disease in certain patients. It is important: With every order of a pack of Advair rotacaps you get a rotahaler for free.
Generic Advair Rotacaps acts locally in the lung tissue. Its content in the blood plasma is not an indication of therapeutic effects.
Lower concentrations of fluticasone propionate in plasma have asthma patients.
Systemic absorption occurs predominantly through the lungs. At first it faster, but then it slows down the speed. Part of the inhalation dose can be swallowed.
With increasing doses of inhaled it is observed linear increase in the concentration of fluticasone propionate in plasma.
It is used only as an inhalation.
The physician should inform the patient that the drug should be used regularly, even in the absence of clinical symptoms of asthma and COPD.
The doctor should monitor the effectiveness of treatment.
Determination of the duration of therapy and change in dosage is possible only on the advice of a doctor.
After the inhaler you should rinse your mouth with water and then spit it out. You must comply the doctor’s instructions, using an inhaler. Contact your doctor if you have any difficulty using an inhaler.
Young children can not themselves use an inhaler, and adults should help them.
You should clean the inhaler at least once a week.
All adverse events reported below are typical for active substances — salmeterol and fluticasone.
Data from clinical studies:
Infectious and parasitic diseases: often — candidiasis of the oral cavity and pharynx, pneumonia (in patients with COPD).
Immune system: hypersensitivity reactions: rarely — skin hypersensitivity reactions, shortness of breath, rarely — anaphylactic reactions.
From endocrine system: possible systemic effects include: Infrequent — cataract, rarely — glaucoma.
Metabolism and nutrition: rarely — hyperglycemia; very rarely — hypokalemia.
Mental disorders: rare — anxiety, sleep disorders; rarely — changes in behavior, including hyperactivity and irritability (especially in children).
From the nervous system: very often — headache; infrequently — tremor.
From the heart: Infrequent — palpitation, tachycardia, atrial fibrillation; rarely — arrhythmias, including ventricular arrhythmia, supraventricular tachycardia and arrhythmia.
The respiratory system, organs, thoracic and mediastinal disorders: common — hoarseness and / or hoarseness; infrequently — throat irritation.
Skin and subcutaneous tissue disorders: rarely — bruising.
Musculoskeletal and connective tissue disorders: common — muscle cramps, arthralgia.
Immune system: hypersensitivity reactions: seldom — angioedema (mainly facial swelling and oropharynx), bronchospasm.
From endocrine system: possible systemic effects include rare — Cushing’s syndrome, Cushingoid symptoms, adrenal suppression, growth retardation in children and adolescents, decrease in bone mineral density.
The respiratory system, organs, thoracic and mediastinal disorders: rarely — paradoxical bronchospasm.
Indications for use:
The drug is intended for the regular treatment of asthma, if necessary combination therapy.
Contraindications Generic Advair Rotacaps:
— Children under 4 years of age;
— Hypersensitivity to the drug.
Generic Advair Rotacaps sold by prescription.
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