Evista (Raloxifene). Cheapest Evista pills

Drug Information: Indications, Side Effects, Warnings

Category:  Osteoporosis, Women’s Health, Cancer

Generic Evista is used for treating and preventing osteoporosis (bone thinning) in women, who are past menopause. Evista also used to reduce the risk of invasive breast cancer in certain women, who are past menopause.pills Evista 60 mg

Pharmacological action:

Generic Evista is a selective estrogen receptor modulator. The drug acts as an agonist on the tissues of the body, not related to reproduction. And as antagonist — on reproductive tissues. Effect is due to high affinity binding to estrogen receptors and regulation of gene expression.

— Reduces the process of bone resorption:
— Normalizes the calcium balance in the body (by reducing calcium loss in the urine).
— Does not cause endometrial proliferation, increase the size of the uterus, bleeding or postmenopausal bleeding.
— No effect on the occurrence of endometrial cancer de novo.
— Do not induce hyperplasia of mammary tissue.
— Reduces swelling and breast tenderness.
— Reduces the levels of total and LDL cholesterol.
— HDL cholesterol and triglycerides did not change.
— It reduces the content of blood plasma fibrinogen.

Pharmacokinetics:

— Rapidly absorbed from the gastrointestinal tract after oral administration.
— Are extensively metabolized by glucuronidation the «first pass» through the liver.
— 3 conjugated metabolites determined in plasma.
— The absolute bioavailability of raloxifene is 2%.
— It is widely distributed in the body.
— Vd not dose-dependent. Plasma protein binding is 98-99%.
— Level of raloxifene maintained by enterohepatic recycling. T1 / 2 of 27.7 hours.
— Most of the dose was excreted within 5 days from the feces. Less than 5% is excreted in the urine (in the form of unchanged substance and metabolite).

Dosage:

The ingestion dose is 60 mg / day. Treatment is long.

When used in elderly patients, correction dose is not required.

Pregnancy and lactation:

-Only for use in post-menopausal women.
— Can have a damaging effect on the fetus.
— May have a negative impact on child development, so stop breastfeeding during treatment.

In renal impairment:

Is contraindicated in severe renal impairment.

If abnormal liver function:

it is Contraindicated in liver disease (including cholestasis).

Evista Side effects hair loss:

With the blood coagulation system: a small thrombocytopenia; rarely — venous thromboembolism (including deep vein thrombosis), pulmonary embolism, retinal vein thrombosis.

On the part of the circulatory system: vasodilation (feeling of heat).

Other: calf muscle cramps, peripheral edema.

 

Indications for use:

Prevention of osteoporosis in post-menopausal women.
Contraindications:

Thromboembolism, including deep vein thrombosis, pulmonary embolism, and retinal vein thrombosis, liver disease (including cholestasis), severe renal dysfunction, uterine bleeding of unknown etiology, breast cancer, endometrial cancer, increased sensitivity to raloxifene.

 

Where can I buy Generic Evista (Raloxifene)?

You can buy Generic Evista in pharmacy or online store.

How to buy cheaper?

You can buy Generic Evista, using a coupon or discount cards. Discount is of 20-80%. Watch out for the shares. Some pharmacies make sales.

Can I buy without a prescription?

Yes I Am. Often when you order online, prescription is not required.

Prices for 30 tablets of generic raloxifene 5-100 mg

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