Kemadrin: symptomatic treatment of Parkinson’s

Necessary Information about Kemadrin

Kemadrin is indicated to treat symptoms of Parkinson’s disease such as tremors, stiffness, spasms, and poor muscle control.

Synonyms: Apricolin, Kemadren, Kemadrin, Metanin, Osnervan, Procyclid.






Hypersensitivity, angle-closure glaucoma, liver and / or kidney failure, fever.


Separate, scheme. The daily dose for adults: 2-6 tablets, the average dose — 3-4 tablets; children up to 3 years — 0.5-2 tablets, the average dose — 1-1.5 tablets; 3-8 years — 2-4 tablets, the average dose — 2-2.5 tablets; 8-14 years — 3-6 tablets per day, average dose — 3-4 tablets.

Scheme of use:

1. The initial dose of 0.5 tablets in the evening reception,

2. On the third day of therapy added 0.5 tablets in the morning reception,

3. On the fifth day added 0.5 tablets daily intake

4. Continue to increase the daily dose of 0.5 tablets every 2 days

5. The 15 day morning dose therapy sostavit1.5 tablets daily — 1 tablet and evening — 1.5 tablets;

This mode remains unchanged up to 20 days. increase the dose if necessary. Tablets are taken after a meal.

Side effects

Dry mouth, paresis of accommodation, mydriasis, dizziness.

Special instructions:

Patients with glaucoma need to control intraocular pressure. During treatment should avoid activities requiring increased rate of mental and motor responses.

From the nervous system: tremor, ataxia, dysarthria, diplopia, irritability, insomnia, dizziness.

From the senses: nystagmus, eye pain.

From the digestive redundant system: gastritis, loss of appetite, nausea, vomiting, gastralgia.

From the side of hematopoiesis: leukopenia, aplastic anemia, megaloblastic, B12-deficiency anemia, agranulocytosis, lymphadenopathy.

Allergic reactions: skin rash, fever, exfoliative dermatitis hepatitis.

Other: polyarthritis, gingival hyperplasia, weight loss, changes in connective tissue (coarsening of facial features, Dupuytren’s contracture), teratogenic effects in the form of facial deformities of the skull, skeletal deformities and heart disease; long-term use (2-5 months) — breach of calcium-phosphorus metabolism, latent osteopathy.

With prolonged use, possible manifestations of the syndrome of hypersensitivity to the drug and marked depression of the central nervous system, this requires its cancellation.