Everything you want to know about the drug Lotrel

Active substance

Amlodipine

Pharmacological group:

Calcium channel blockers

Indications for use

Lotrel is the brand name of a prescription medicine containing the drugs amlodipine and benazepril. It's used to treat high blood pressure.

Lotrel is the brand name of a prescription medicine containing the drugs amlodipine and benazepril. It’s used to treat high blood pressure.

Arterial hypertension (monotherapy or in combination with other antihypertensive drugs); stable angina pectoris and vasospastic (Prinzmetal); including in patients resistant to therapy with nitrates or beta-blockers.

Contraindications

Hypersensitivity (including to other dihydropyridine), hypotension (less than 90 mm Hg. Art.), Shock, acute myocardial infarction (including the period of 1 month after).

Category effects on the fetus by FDA — C.

At the time of treatment: should stop breastfeeding.

Side effects

Cardio-vascular system and blood (blood, hemostasis): facial flushing, palpitations; rarely — arrhythmias (bradycardia, ventricular tachycardia, atrial flutter), chest pain, hypotension (including orthostatic).

From the nervous system and sensory organs: fatigue, headache, dizziness, drowsiness; rarely — fatigue, fatigue, mood changes, visual disturbances.

From the urogenital system: peripheral edema (swelling of the ankles and feet); rarely — increased urinary frequency, impotence.

From the digestive tract: nausea, stomach pain; rarely — indigestion, change in bowel movement mode, jaundice.

From the respiratory system: rarely — shortness of breath.

From the musculoskeletal system: rarely — arthralgia, myalgia, paresthesia and pain in the extremities (with prolonged use).

For the skin: rash, pruritus, rarely — erythema multiforme.

Other: rarely — gingival hyperplasia, gynaecomastia, increase in liver enzymes.

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Precautionary measures

With careful use: during the drivers of vehicles and people skills relate to the high concentration of attention (at the beginning of treatment may be dizziness and drowsiness).

Dosage

For adults, ingestion: starting dose is 5 mg 1 times / day. the dose may be increased if necessary.

Maximum dose: at intake — 10 mg / day.

Release form, composition and packing

Tablets are white to off-white, round, flat with beveled edges.

Table 1 .: amlodipine (in the besylate salt form) — 10 mg

Excipients: microcrystalline cellulose, silicate, pregelatinized starch, magnesium stearate.

10 pieces. — Blisters (2) — packs cardboard.

Tablets are white to off-white, round, flat with beveled edges.

1 tablet: amlodipine (in the besylate salt form) — 5 mg

Excipients: microcrystalline cellulose, silicate, pregelatinized starch, magnesium stearate.

10 pieces. — Blisters (2) — packs cardboard.