Drug Information: Indications, Side Effects, Warnings
Generic Imitrex is used for the treatment of migraine headaches with or without aura (eg, flashing lights, wavy lines, dark spots).
You can buy Generic Imitrex in the pharmacy with a prescription (or without a prescription) or order online. If you want to buy a cheaper drug, use a coupon or discount cards. Pharmacies offer their customers discounts and promotions.
The main substance Generic Imitrex ‚Äď Sumatriptan
Nosological classification (ICD-10):
-G43.0 Migraine without aura [simple migraine]
-G43.1 Migraine with aura [classical migraine]
Pharmacological action — protivomigrenoznoe.
— Interaction with the 5-HT1-receptors mainly in the blood vessels of the brain (stimulation of 5-HT1-receptors leads to a narrowing of blood vessels).
— Selectively excite the serotonin 5-HT1D-receptors vessels of the brain (dura mater of the basilar artery)
— Generic Imitrex inhibits activation of trigeminal system
— Reduces the accumulation of specific stimulatory protein in the nuclei of the trigeminal nerve
— Generic Imitrex activates serotonergic brainstem antinociceptive mechanisms.
— The drug causes vasoconstriction and stop the attack.
— Stops the development of a migraine attack, without possessing a direct analgesic effect.
Indications for use:
Relief of migraine (with or without aura).
You should inform your doctor about conditions such as:
Hypersensitivity, hemiplegic, basilar or oftalmoplegi—Ā form of migraine, myocardial infarction (including history), uncontrolled hypertension, ischemic heart disease (including suspected it), angina pectoris, including Prinzmetal angina, occlusive peripheral vascular disease, transient ischemic attack (including history), stroke (including history, drug imitrex interaction), expressed as the liver and / or kidney disease, concomitant use of sumatriptan with ergotamine or its derivatives (including methysergide) and simultaneous MAO inhibitors and the period up to 2 weeks after their withdrawal.
Restrictions apply to:
Epilepsy (including any state with a reduction in the threshold of convulsive readiness), hypertension (controlled), pregnancy, lactation, age 18 years (safety and efficacy not established), age over 65 years (experience of limited).
From the nervous system and sensory organs: Frequent: dizziness, weakness and / or fatigue (usually by ingestion), drowsiness (usually mild to moderate and are transient in nature). Seek medical attention immediately.
— In some cases — seizures (usually in the presence of a history of seizures or with conditions predisposing to seizures);
— sometimes — diplopia, flickering flies in front of the eyes, nystagmus, scotoma, reduced visual acuity; rarely — partial transient loss of vision (visual impairment may be associated with a migraine attack itself).
Cardio-vascular system and blood (blood, hemostasis):
Often: lowering blood pressure, a temporary increase in blood pressure (observed shortly after admission), bradycardia, tachycardia (including ventricular), palpitations — Requires monitoring tests;
— in some cases — cardiac arrhythmia (up to ventricular fibrillation), transient ischemic ECG changes such as myocardial infarction, coronary artery spasm;
— sometimes develops Raynaud’s syndrome.
From the digestive tract: often nausea and vomiting (usually by ingestion), a slight increase in liver enzymes, dysphagia, abdominal discomfort;
— rarely — ischemic colitis.
Hypersensitivity reactions: Common: skin manifestations (rash, urticaria, pruritus, erythema); in rare cases — anaphylaxis. Seek medical attention immediately.
Other: pain, tingling, heat sensation, a feeling of pressure or heaviness (usually transient, but can be intense and occur in any part of the body including the chest and throat), myalgia, flushing.
The drug is not used to prevent migraines. The drug is given, if the diagnosis is not in doubt.
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