Lithobid: Indications for use, Dosage, Nosological Classification

The nosological classification (ICD-10)

F10.2 alcohol dependence syndrome

F25 Schizoaffective disorders

F30 Manic episode

F30.0 Hypomania

F31 Bipolar affective disorder

F65 Disorders of sexual preference

G43 Migraine

H81.0 MĂ©nière’s Disease

Y57.9 Adverse effects in therapeutic use of drugs and medicines unspecified

Lithobid is used to treat bipolar disorder. Dosage Form: capsules, coated tablets, prolonged action tablets.



Indications for use

Manic and hypomanic state of various origins, affective psychoses (manic-depressive, schizoaffective), alcoholism (affective disorders); migraine, Meniere’s syndrome, sexual dysfunction, drug dependency (some forms).


Hypersensitivity, severe surgery; leukemia, pregnancy, laktatsii.S caution. Diseases of the CAS (including AV block, intraventricular block), CNS disorders (epilepsy, Parkinson’s disease), diabetes, hyperthyroidism, hyperparathyroidism, infection, psoriasis, renal failure, urinary retention, disruption of water and electrolyte metabolism (dehydration — simultaneous treatment diuretics, salt-free diet, delay Na +, vomiting, diarrhea).




Inside (for 3-4 doses, the last time — before going to bed), after a meal, the initial dose — 0.6-0.9 g / day. The gradual increase: of up to 1.2 g / day. Dose daily: increase of 0.3 g to 1.5-2.1, the maximum daily dose — 2.4 g.

During the selection of therapy, the concentration of Li + in plasma should be greater than 0.6 and less than 1.2-1.6 mmol / l. Duration of treatment — 1-2 weeks.

Side effects of substance

From the nervous system and sensory organs: hand tremor, drowsiness, weakness.

Cardio-vascular system and blood (blood, hemostasis): irregular heartbeat, leukocytosis, inhibition of hematopoiesis.

From the digestive tract: diarrhea, nausea, vomiting, dry mouth.

With the genitourinary system: polyuria, renal dysfunction.

Other: myasthenia gravis, increased thirst, weight gain, hypothyroidism, allergies, alopecia, acne.

Side effects of Lithobid

Dyspepsia, discomfort, male, hand tremor, arrhythmia, drowsiness, increased thirst, arrhythmia, inhibition of hematopoiesis, hypothyroidism, leukocytosis, increased tela.Peredozirovka mass. Symptoms: Early — diarrhea, drowsiness, loss of appetite, muscle weakness, nausea, vomiting, dysarthria, tremor; Later — dizziness, blurred vision, impaired coordination of movement, polyuria, confusion, severe cramps. Treatment: As a first aid expedient introduction into a large amount of fluid and Na +; in severe cases require hospitalization.

Precautionary measures

Do not use:

for violations of water-salt balance (salt-free diet, sodium deficiency, diarrhea, vomiting).

To use caution:

  • diabetes (serum insulin concentration may be increased)
  • hypothyroidism.