Micardis: Instructions for use, contraindications, composition and price

Active substance

Telmisartan

Therapeutic

Angiotensin II receptor antagonists (AT1-subtype)

The nosological classification (ICD-10)

I10 Essential (primary) hypertension

I15 Secondary hypertension

I15.0 Renovascular hypertension

Micardis

Micardis

The drug forms

Tablets 40 mg: white or almost white, oblong shaped tablets; one side applied marking «51H», on the other side — the symbol of the company.

Tablets 80 mg: white or almost white, oblong shaped tablets; one side applied marking «52H», on the other side — the symbol of the company.

Pharmachologic effect

Mode of action — hypotensive.

The active ingredient blocks receptors of angiotensin II (type AT1) and eliminates its vasoconstrictor effect. It reduces systemic blood pressure, plasma aldosterone concentration.

Indications

Arterial hypertension.

Contraindications

Hypersensitivity, disorders of the biliary tract patency, expressed human liver or kidney disease, hereditary fructose intolerance, pregnancy, breastfeeding, childhood and adolescence.

Pregnancy and breast-feeding

Contraindicated during pregnancy. At the time of treatment should stop breastfeeding.

Side effects

From the nervous system: headache, dizziness, fatigue, insomnia, anxiety, depression, convulsions.

The respiratory system: upper respiratory tract infection (including pharyngitis, sinusitis, bronchitis), cough.

Cardio-vascular system: marked reduction of blood pressure, bradycardia, tachycardia, chest pain.

From the digestive system: nausea, dyspepsia, diarrhea, abdominal pain, increased activity of «liver» transaminases.

From the musculoskeletal system: myalgia, arthralgia, back pain, tendonitis like symptoms.

From the urinary system: peripheral edema, urinary tract infection, hypercreatininemia.

Allergic reactions: skin rash, and others.

Laboratory findings: rarely — hyperkalemia, hyperuricemia, or anemia.

Other: flu-like symptoms, rarely — erythema, pruritus, syncope, dyspnoea, eosinophilia, thrombocytopenia, angioedema, urticaria.

Overdose

Symptoms: marked reduction of blood pressure.

Treatment: symptomatic therapy; Hemodialysis is ineffective.