Drug Information: Indications, Side Effects, Warnings
Adalat Cc (Nifedipine)
Category:Â Hypertension,Â Cardiovascular Diseases
Generic Adalat CC Extended-Release is used for treating high blood pressure.
Brands: Nicardia CD / Nicardia Retard / Nicardia XL
Generic Adalat Cc is a selective blocker of the «slow» calcium channels. The drug has antianginal and hypotensive action. The drug lowers the tone of smooth muscles of coronary arteries. Generic Adalat Cc rapidly and almost completely absorbed from the gastrointestinal tract. Nifedipine is metabolized in the intestinal wall and liver. As a result, inactive metabolites formed.
-Symptoms: impaired consciousness up to coma, a sharp drop in blood pressure, heart rhythm disturbances — tachycardia / bradycardia, hyperglycemia, metabolic acidosis, hypoxia.
-Cardiogenic shock, accompanied by pulmonary edema.
Treatment: gastric lavage.
The drug is contraindicated in pregnancy and lactation.
The frequency of> 1% <0%
-Common: asthenia (fatigue), swelling of the lower extremities.
-Cardiovascular system: vasodilation (flushing, heat sensation), palpitations, peripheral edema.
-Digestive system: nausea.
-Nervous system: dizziness, headache.
-The incidence of Â > 0.1% < 1.0%
-Common: abdominal pain, chest, feeling of malaise.
-Cardiovascular System: angina pectoris, postural hypotension, tachycardia, syncope.
-Digestive system: constipation, diarrhea, dryness of the mouth, dyspepsia, vomiting.
— Musculoskeletal System: myalgia, arthralgia.
- Nervous system: insomnia, irritability, paresthesia, somnolence, tremor, dizziness.
— Respiratory: dyspnea.
— Skin: sweating, itching, rash, redness of the skin.
-The urinary system: polyuria, nocturia.
The incidence of> 0.01% <0.1%
General: an increase in the abdomen due to subcutaneous fat, allergic reactions, photosensitivity reactions.
Cardiovascular system: marked reduction of blood pressure.
Digestive System: gastrointestinal disorders, flatulence, changes in transaminase levels, elevated levels of gamma-glutamyl.
Nervous system: hypersensitivity.
Blood and hematopoietic system: purpura (thrombocytopenia).
Senses: visual disturbances, ambilopiya.
The urinary system: frequent urination.
The incidence of <0.01%
Digestive system: gingival hyperplasia.
Blood and hematopoietic system: agranulocytosis.
Skin: eritromelalgiya, exfoliative dermatitis.
Other: allergic reactions (anaphylaxis), gynecomastia.
Conditions and terms:
The drug should be stored at a temperature not exceeding 30 Â° C, protected from light, dry and away from children.
Indications for use:
— Coronary heart disease: chronic stable angina (angina of effort).
— Hypersensitivity to nifedipine and other dihydropyridine derivatives 1.4;
— Cardiovascular shock.
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