Protonix is the anti-ulcer, reducing the acidity of the gastric drug, a proton pump inhibitor. The active substance is pantoprazole. Protonix decreases a ruining effect of stomach acid on mucous of esophagus and used to heal erosive esophagitis.
Main ingredient: Pantoprazole
Indications for use
Gastric ulcer or duodenal ulcer in the acute phase, Zollinger-Ellison syndrome, eradication of Helicobacter pylori (in combination with antibiotic therapy), reflux esophagitis.
Therapeutic of Protonix
proton pump inhibitors
The nosological classification (ICD-10) of Protonix
K21 Gastroesophageal reflux
K25 Gastric ulcer
K26 Duodenal Ulcer
K27 Peptic ulcer, unspecified
K86.8.3 * Zollinger-Ellison Syndrome
How to use Protonix. Read the Medication Guide provided by your pharmacist before you start taking pantoprazole and each time you get a refill.
Application of Protonix
Duodenal ulcer or stomach in the acute phase, including associated with NSAID, or refractory to therapy with histamine H2-receptor; gastroesophageal reflux disease (moderate and severe); Zollinger-Ellison syndrome; Combined H. pylori eradication therapy in patients with peptic ulcer to reduce the frequency of relapses.
Contraindications of Protonix
Hypersensitivity, hepatitis and cirrhosis of the liver, accompanied by severe hepatic insufficiency.
Abnormal liver function, children’s age (application experience in children under 6 years old is absent).
From the digestive tract: diarrhea; rarely — dry mouth, increased appetite, nausea, belching, vomiting, flatulence, abdominal pain, constipation, increased activity of transaminases, gastrointestinal carcinoma (single instance).
From the nervous system and sensory organs: headache; rarely — fatigue, dizziness, somnolence, insomnia; in some cases — anxiety, depression, tremor, paresthesia, photophobia, blurred vision, tinnitus.
With the genitourinary system: in rare cases — hematuria, edema, impotence.
Skin: in rare cases — alopecia, acne, exfoliative dermatitis.
Allergic reactions: seldom — rash, urticaria, pruritus, angioedema.
Other: rarely — hyperglycemia, myalgia; in rare cases — fever, eosinophilia, hyperlipoproteinemia, hypercholesterolemia.
The average therapeutic dose is 40 mg / day. The maximum daily dose is 80 mg. Duration of therapy is set depending on the evidence, but it should not exceed 8 weeks.
Overdose of Protonix
Symptoms are not described.
Treatment: It is recommended carrying out a supportive and symptomatic therapy for suspected overdose. Dialysis is ineffective.