Instructions for use, contraindications, composition and price of Nexium

Nexium reduces amount of acid in the stomach and helps patients with gastroesophageal reflux disease and Zollinger-Ellison syndrome. Active ingredient: Esomeprazole

The nosological classification (ICD-10) of Nexium

K21.0 Gastro-oesophageal reflux with oesophagitis
K25 Gastric ulcer
K26 Duodenal Ulcer
K31.8.2 * gastric hyperacidity
K86.8.3 * Zollinger-Ellison Syndrome
K92.2 Gastro-intestinal bleeding, unspecified
Y45 adverse reactions in therapeutic use of analgesic, antipyretic and anti-inflammatory agents

nexium

nexium

The drug forms of Nexium

Tablets 20 mg: oblong biconvex, light pink, film-coated, engraved with «20 mg» on one side and «A / EH» — on the other.

Tablets 40 mg: oblong biconvex, pink, film-coated, engraved with «40 mg» on one side and «A / EI» — on the other.

Color on a break — white with yellow patches (cereal type).

Indications for use of Nexium

gastroesophageal reflux disease:

— Treatment of erosive reflux esophagitis;

— Long-term maintenance therapy after healing of erosive reflux esophagitis to prevent relapse;

— Symptomatic treatment of gastroesophageal reflux disease;

gastric ulcer and duodenal ulcer (in a combination therapy):

— Treatment of duodenal ulcer associated with Helicobacter pylori;

— Prevention of relapse of peptic ulcers associated with Helicobacter pylori;

long-term therapy in patients undergoing bleeding from peptic ulcers (after / in the use of drugs, reducing the secretion of gastric glands) for relapse prevention;

Patients taking NSAIDs for a long time:

— Healing of gastric ulcers associated with NSAID;

— Prevention of gastric and duodenal ulcers associated with NSAIDs, in patients at risk;

Zollinger-Ellison syndrome and other conditions characterized by pathological hypersecretion of gastric glands, including idiopathic hypersecretion.

nexium

nexium

Contraindications of Nexium

Hypersensitivity to esomeprazole, substituted benzimidazoles or other ingredients included in the formulation;

hereditary fructose intolerance, glucose-galactose malabsorption or sucrase-izomaltaznaya failure;

concomitant use with atazanavir and nelfinavir (see «Interaction».);

Children up to age 12 years (due to lack of data on efficacy and safety of the drug in this patient group);

children older than 12 years (for other indications, except gastroesophageal reflux disease).

Precautions: severe renal insufficiency (application experience is limited).

Side effects of Nexium

The frequency of side effects is given by the following grading: very common (≥1 / 10); commonly (≥1 / 100, <1/10); uncommon (≥1 / 1000, <1/100); rare (≥1 / 10,000, <1/1000); very rare (<1/10000).

Skin and subcutaneous tissue disorders: uncommon — dermatitis, pruritus, rash, urticaria; rare — alopecia, photosensitivity; very rarely — erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis.

On the part of the musculoskeletal and connective tissue disorders: rarely — arthralgia, myalgia; rarely — muscle weakness.

From the nervous system: often — headache; Infrequent — dizziness, paresthesia, drowsiness; rarely — a violation of taste.

Mental disorders: rarely — insomnia; rarely — depression, agitation, confusion; very rarely — hallucinations, aggressive behavior.

On the part of the digestive tract: often — abdominal pain, constipation, diarrhea, flatulence, nausea / vomiting; Infrequent — dry mouth; rarely — stomatitis, gastrointestinal candidiasis; very rarely — microscopic colitis.

On the part of the liver and biliary tract: rarely — increase in liver enzymes; rarely — hepatitis (with or without jaundice); very rarely — liver failure, encephalopathy in patients with liver disease.

From the genitals and breast: it is very rare — a gynecomastia.

From the blood and lymphatic system: rarely — leukopenia, thrombocytopenia; very rarely — agranulocytosis, pancytopenia.

Immune system: rarely — hypersensitivity reactions (eg fever, angioedema, anaphylactic reaction / anaphylactic shock).

The respiratory system, organs, thoracic and mediastinal disorders: rarely — bronchospasm.

On the part of the kidney and urinary tract: very rarely — interstitial nephritis.

On the part of the organ of vision: rarely — blurred vision.

On the part of metabolism and nutrition: rarely — peripheral edema; rarely — hyponatremia; very rarely — hypomagnesemia; hypocalcemia due to severe hypomagnesemia, hypokalemia, hypomagnesemia due.

General disorders: rarely — malaise, sweating.