Singulair blocks substances in the body called leukotrienes, which are responsible for development of asthma and allergic rhinitis. Singulair is a leukotriene (loo-koe-TRY-een) inhibitor which used for the treatment of asthma, the prevention of exercise-induced asthma, and allergic rhinitis (sneezing, stuffy nose, runny nose, itching of the nose, and outdoor and indoor allergies). Singulair blocks substances in the body called leukotrienes, which cause asthma and allergic rhinitis.
Pharmacological group of Singulair
Prostaglandins, thromboxanes, leukotrienes and their antagonists
Structure and Composition of Singulair
1 tablet or chewable tablet, coated tablet. Contains: montelukast 5 mg or 10 mg, respectively; in blister 7 pcs., in box 2 of the blister.
Indications for use Singulair
Prevention and long-term treatment of asthma in adults and children aged 6 years and older, including:
— Prevention of daytime and nighttime symptoms of the disease;
— The treatment of asthma in patients with hypersensitivity to acetylsalicylic acid;
— Warning the bronchospasm caused by exercise.
Relief of daytime and nighttime symptoms of seasonal allergic rhinitis (in adults and children aged 6 years and older) and perennial allergic rhinitis (in adults and children aged 6 years and older).
Before using the medication please consult with your doctor to avoid overdose Singulair and not cause a complication of the disease. You will get best result using it every day. Swallow the tablet whole with a glass of water/milk. If you are taking the chewable tablet, the tablet must be chewed before swallowed.
Contraindications of Singulair
— Children up to age 6 years;
— Hypersensitivity to the drug.
Side effects of Singulair
Infectious and parasitic diseases: upper respiratory tract infection.
Co the blood coagulation system: increased tendency to bleeding.
Immune system: hypersensitivity reactions, including anaphylaxis; very rare (<1/10 000) — eosinophilic infiltration of the liver.
On the part of the psyche: agitation (including aggressive behavior or hostility), anxiety, depression, disorientation, impaired attention, abnormal dreams, hallucinations, insomnia, memory impairment, psychomotor activity (including irritability, restlessness, and tremor), somnambulism, suicidal thoughts and behavior (suicidality).
From the nervous system: dizziness, somnolence, paresthesia / hypoesthesia; very rare (<1/10 000) — cramps.
Since the cardiovascular system: heart palpitations.
Respiratory system: epistaxis.
From the digestive system: diarrhea, dyspepsia, nausea, vomiting, pancreatitis.
On the part of the liver and biliary tract: increased activity of ALT and ACT in the blood; very rare (<1/10 000) — hepatitis (including cholestatic, hepatocellular, and mixed liver injury).
Skin and subcutaneous tissue disorders: a tendency to the formation of hematomas, erythema nodosum, erythema multiforme, pruritus, rash.
Allergic reactions: angioedema, urticaria.
From the Musculoskeletal System: arthralgia, myalgia including muscle cramps.
General reaction: asthenia (weakness) / fatigue, edema, pyrexia.
In general, Singulair drug was well tolerated. Side effects are usually mild and usually do not require discontinuation of therapy. The overall incidence of side effects in the treatment of drug Singulair is comparable to the frequency of placebo.
The use in the elderly
For elderly patients a special dose adjustment is required.
Application of Singulair in childhood
Contraindications: Children under 6 years old. Children aged 6 to 14 years is prescribed at a dose of 5 mg (1 tab. Chewing) / day. Dose selection in this age group is not required.