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Drug Information: Indications, Side Effects, Warnings

Category:  Antivirals

The drug is used to treat multidrug-resistant tuberculosis (in combination with anti-TB drugs) and leprosy. Generic Lamprene has a bacteriostatic and bactericidal effect on Mycobacterium leprae, and also has anti-inflammatory effect.

You can buy Generic Lamprene (Clofazimine) at the pharmacy or order online. You can buy cheap Generic Lamprene (Clofazimine), using a coupon or discount cards.Lamprene

Dosage

Tuberculosis: adults: 100 mg 1 time per day during or directly after a meal, children weighing more than 50 kg: 1 mg / kg body weight per day. Multibakterialni forms of leprosy: Adults: 300 mg 1 time per month. 1 and 50 mg once daily as maintenance therapy in combination with rifampicin 600 mg 1 time per month and diafenilsulfonom: 100 mg 1 time per day as maintenance therapy for children 150 mg 1 time per month. and 50 mg a day as maintenance therapy in combination with rifampicin 450 mg 1 time per month and diafenilsulfonom: 50 mg 1 time per day as maintenance therapy. The duration of combination treatment — 12 months. Erythema nodosum leprosy: Adults and children weighing more than 50 kg: treatment.

Indications

Clofazimine (in combination with rifampicin and dapsone) is used to treat leprosy polibatsillyarnyh forms, including lepromatous type border lepromatous group Border leprosy (Ridley and classification Jopling), as well as erithema nodosum leprosum. In the treatment must be performed combination chemotherapy to prevent stable stamps M. leprae.

Contraindications

Hypersensitivity to the drug, a history of photosensitivity, pregnancy and breast feeding, body weight less than 50 kg.

Side effects

  1. Change the color of the hair, conjunctiva, cornea, lacrimal fluid, sweat, sputum, urine and feces.
  2. Dry skin, ichthyosis, pruritus, photosensitivity, acne-like rash, and non-specific rash
  3. Nausea, vomiting, stomach pain, diarrhea, anorexia, weight loss and eosinophilic enteropathy.

Serious side effects include: progressive weight loss, anorexia, intermittent, prolonged diarrhea.

Composition

1 capsule contains 50 mg or 100 clofazimine;

Excipients: lactose, microcrystalline cellulose, sodium croscarmellose, colloidal silica, povidone K-30, purified water, magnesium stearate, talc.

Therapeutic

Medications for mycobacteria. ATC code J04B A01. Generic price lamprene.

The drug should not be taken simultaneously with: sulfonamides, streptomycin, tetracycline, gentamicin, monomitsin, neomycin, amphotericin B, polymyxin M tseporin other cephalosporins, heavy metals and their compounds (mercury, lead, cadmium), chetirohhloristy carbon dichloroethane.

The drug is active against Mycobacterium tuberculosis, leprosy, as well as a number of other mycobacteria.

 

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