Drug Information: Indications, Side Effects, Warnings
Category: Â Antifungals
Generic Lamisil is an antifungal antibiotic.
Therapeutic agents Terbinafine
Nosological classification (ICD-10)
B35.0 Mycosis beards and heads
B35.1 Mycosis Nails
B37.2 Candidiasis skin and nails
Athlete’s foot, unspecified B49
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Characteristics of matter
Antifungal agent for oral and topical use. Terbinafine hydrochloride — synthetic derivative of allylamine, white or almost white crystalline powder, freely soluble in methylene chloride and methanol, soluble in ethanol, is sparingly soluble in water. The molecular weight is of 327.90.
Mode of action is antifungal, fungicidal.
— Has an effect on dermatophytes, yeast and mold fungi. — It affects the cytoplasmic membrane of fungal cells
— Specifically inhibits squalene epoxidase
— Violates the synthesis of ergosterol, causing a fungicidal effect.
— The drug is active against almost all fungi, pathogenic to humans, but most of all — red Trichophyton (minimum inhibitory concentration is 0,001-0,06 ug / ml).
The drug is active against pathogenic yeasts — molds, pitiriazisa and filamentous forms of the genus Candida.
The drug is rapidly absorbed from the gastrointestinal tract.
Indications for use
Fungal skin, hair and nails, candidiasis of the skin and mucous membranes.
Hypersensitivity expressed hepatocellular and renal failure, blood diseases, tumors, metabolic diseases, vascular pathology of extremities, pregnancy, lactation, children’s age (up to 2 years).
Heaviness and pain in the epigastric region, taste disturbance, loss of appetite, nausea, diarrhea, cholestasis, neutropenia, thrombocytopenia, allergic skin reactions.
The method of use and dose (lamisil tablet and alcohol):
Inside, the food, 1 times a day in the evening in the dose of 250 mg or 2 times daily 125 mg.
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