Asendin is a part of the group of tricyclic antidepressants

Uses Asendin

Asendin is a part of the group of tricyclic antidepressants, which treat depression. Compared with other antidepressants, it has a rapid onset of action. This drug is developed by American pharmaceutical company Lederle Laboratories. This company was a part of American Cyanamid Company, American conglomerate. It produces high quality products. The main ingredient of this drug has an effect on mental status; it helps to cope with depressive condition. However, this medicament has different contra indications such as hypersensitivity and serious cardiovascular disease. Also it has many side effects. Therefore, at the outset, you should consult your specialist and get prescription. This drug is available only on prescription. Be careful taking this medicament and try to avoid overdose.



Brand(s): Asendin, Amoxapine.

Manufacturer(s): Lederle Laboratories, USA.

Clinico-pharmacological group: This drug is a part of the group of tricyclic antidepressants, belongs to average serotonin reuptake inhibitor and acute noradrenaline reuptake inhibitor. It includes the basic ingredient amoxapine. Therefore, this medicament treats depression and different mental disorders.

Composition, structure and packing: This medicament comes in seven-sided and round tablets. Tablets are white or orange-yellow color.

Basic ingredient: The main component of this drug is amoxapine. This ingredient has an effect on mental status. That is why it is used in treatment of depression.

Other ingredients: Asendin includes inactive components such as:

  • Starch;
  • Calcium phosphate;
  • Stearic acid;
  • Dibasic, dehydrate;
  • Corn;
  • Magnesium stearate.

The composition of the coating film: It includes titanium dioxide.


You should consult your specialist before you begin to take this medicament. This drug should be used only on doctor’s prescription. In order to avoid possible problems such as side effects and overdose, it is recommended to refrain from taking this medicine without doctor’s instructions. This drug is taken by mouth. As usual, initial dose is 50 milligrams, which you should take 2-3 times a day. Maintenance dose consists 100 milligrams, which you should take 2-3 times a day. Maximal dose is 600 milligrams a day. Doses, which are above 300 milligrams, should be divided into several intakes.


Substance of this medicament is very toxic in case of overdose. There is a real risk to get renal insufficiency, coma, convulsions and etc. Therefore, avoid high doses. Do not self-medicate and always consult your specialist. If you take more than it should be taken, immediately visit your doctor.

Side effects

You can get side effects in case of wrong intake of this medicament and overdose. In order to avoid it, you should follow prescription of your doctor and do not self-medicate. The list of side effects: sedation, dry mouth, constipation, psychic tension, ataxia, blurred vision, swimming of the head, headache, general weakness, nausea, vomiting, nervousness, irregular appetite, excessive sweating, rash, shivering, fast heartbeat, nightmares, anxiety, puffiness, diarrhoeal disease, tympanitis, hypertension syndrome, low blood pressure, faint, tachycardia, irregular period, mydriasis, convulsions, nasal blockage, ringing of the ears, urinary retention, aggression, numbness, impotence, fever, itch, neuroleptic malignant syndrome, apoplectic attack, seminoma, anorexia and others. Do not self-medicate and you will really reduce the risk of these side effects. It is better to follow doctor’s instruction. If you got any side effects, immediately visit doctor.

Indications for use

Amoxapine is prescribed for using in the treatment of agitated depression and depressive-paranoid conditions, as well as anxiety within the neurotic and reactive depression. Compared with other antidepressants, it has a rapid onset of action.

Contra indications

As with FDA antidepressants, this medicament can cause more suicidal ideation for people who are not over 25 years old. This medicament is not recommended for people with hypersensitivity. Refrain from taking this drug in case of serious cardiovascular disease, closed-angle glaucoma and serious postinfarction syndrome. Be careful and do not take this medicament if you have any contra indications. Also you should not take this drug during pregnancy and breastfeeding.

Where to buy?

Asendin treats agitated depression, anxiety and depressive-paranoid conditions. This medicament is produced by Lederle Laboratories, American pharmaceutical company. There are many ways to buy Asendin. You can find this drug at pharmacy or in the Internet. Making order online you can save money and get discount. Also you can get free shipping.