Minomycin has a wide range of antimicrobial activity

Synthetic Minomycin drug refers to a group of antibiotics and has a wide range of antimicrobial activity. Minomycin drug is active against many Gram-positive and Gram-negative germs, spirochaetes, rickettsiae and some other viruses (particularly to the agents of trachoma, psittacosis, lymphogranuloma venereum). Minomycin is effective even against those strains of bacteria which are resistant to streptomycin, penicillin, and sulfonamides.

Minomycin

Minomycin

Pharmachologic effect

The product Minomycin has a powerful antibiotic action. Minomycin directly affects the formation of protein structures in bacterial cells (reducing the rate of amino acid transport links to the lipid chains). As a result, there is a violation of protein synthesis. Minomycin active against pathogens festering, intestinal bacteria, and meningococcal disease. Minomycin is not intended to suppress the anaerobic, acid-fast bacteria, certain strains of staphylococci, fungi and protozoa.

Indications of the drug

wound infection (II phase of wound healing process — no pus, necrotic tissue) caused by susceptible organisms;

burns 2-3-th degree;

nonhealing sores.

Contraindications

idiosyncrasy;

inhibition of bone marrow hematopoiesis;

acute intermittent porphyria;

deficiency of glucose-6-phosphate dehydrogenase;

liver and / or kidney failure;

skin diseases (psoriasis, eczema, mycosis);

pregnancy;

lactation;

neonatal period (up to 4 weeks).

In the absence of osmotic activity (base oil, emulsifier) is not recommended in the first phase of wound healing process (profuse suppuration, pronounced tissue swelling, pain and the presence of necrotic tissue).

Precautions: early childhood; Patients who received prior treatment with cytotoxic drugs or radiotherapy.

Side effects

Allergic reactions: possible skin rash, angioedema.

From the side of hematopoiesis: rarely — reticulocytopenia, leukopenia, granulocytopenia, thrombocytopenia, erythropenia, aplastic anemia, agranulocytosis.

If any of the above in the description of the side effects are compounded by the patient or notice any other side effects not mentioned in the description, you should inform your doctor.