Drug Information: Indications, Side Effects, Warnings
Generic MinocinÂ (Minocycline)
The selling Generic MinocinÂ (Minocycline) is by prescription
Like other tetracyclines, the drug has a bacteriostatic effect on the cells of microorganisms sensitive to it due to reversible inhibition of protein synthesis. Minocycline passes directly through the lipid bilayer membrane of bacterial (or passively diffuses through the channels) and then binds to the 30S-ribosomal subunit joining and blocks them tRNA, thereby preventing synthesis of bacterial proteins and thus further growth and colonization of bacteria.
Generic MinocinÂ (Minocycline) is also an inhibitor of matrix metalloproteinase and therefore has a moderate anti-inflammatory effect in rheumatoid arthritis, is one of the basic resources treatment of this disease, especially in light of its current.
Indications for use:
Bacterial infections caused by susceptible to malaria infections: infections of the upper and lower respiratory tract; psittacosis (acute infectious disease transmitted to humans from birds), psittacosis (acute infectious disease transmitted to humans from birds), urethritis (inflammation of the urethra), Reiter’s syndrome (infectious-allergic disease characterized by a combination of urethritis / inflammation of the urinary tract / conjunctivitis / inflammation of the outer membrane of the eye / and multiple joint damage), conjunctivitis, trachoma (an infectious eye disease that can lead to blindness), sexually transmitted chlamydia; plague, tularemia (acute infectious disease transmitted to humans from animals), anthrax, cholera, brucellosis (an infectious disease transmitted to humans as a rule, from farm animals), relapsing fever (typhus epidemic return — an infectious disease transmitted by ticks and is characterized by numerous , irregular rise in body temperature); infections of skin and soft tissue caused by Streptococcus, Staphylococcusaurens. Treatment of asymptomatic carriers Neisseriameningitidis.
The drug is not used for the treatment of meningococcal infection and to treat any infections caused by Staphylococcusaureus. For patients who are hypersensitive to penicillin, minocycline is used as an alternative drug for the following infections: gonorrhea, listeriosis (infectious animal disease transmitted to man; characterized by numerous lesions in lymph nodes, / the presence of bacteria in the blood without the formation of foci of purulent inflammation in the tissues /) actinomycoses (fungal diseases); infections caused by Clostridium.
How to use:
Before you assign patient drug to determine sensitivity to the hair that caused the disease in this patient. Dose set individually depending on the severity of the infection and the sensitivity of the organism to the drug. The average starting dose for adults is 0.2 g, hereinafter — 0.1 g every 12 h. For children over 8 years administered in an initial dose of 4 mg / kg body weight, hereinafter — 2 mg / kg of body weight every 12 hours. Therapy should be continued for at least 24-48 hours after the improvement of the patient (the disappearance of symptoms and reduction in temperature). Syphilis administered in an initial dose of 0.2 g, further — 0.1 g every 12 hours for 10-15 days. In gonorrhea treatment duration of at least 7 days. In meningococcal carriage of (the presence of the pathogen in the body of meningitis without symptoms of the disease) drug administered in a dose of 0.1 g every 12 hours for 5 days. The drug should be taken 1 hour before eating or 2 hours after eating. Patients with severe renal impairment and / or liver should be prescribed the drug at a lower dose.
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The anorexia (lack of appetite), nausea, vomiting, diarrhea, dysphagia (swallowing disorders), elevated liver enzymes in the blood; an erythematic rash (types of skin rash), increased sensitivity of the skin to sunlight, shown in excessive sunburn; hypersensitivity reactions — urticaria, arthralgia (joint pain), rarely development of an anaphylactic (allergic) shock. You may experience headaches and dizziness, which can independently disappear with continued treatment, and immediately after its termination. If you experience the first signs of skin erythema drug treatment should be discontinued.
Hypersensitivity to tetracyclines, pregnancy. Not indicated for children up to 8 years. The drug should be used with caution in patients with an indication of the allergic reactions in history .
Generic MinocinÂ (Minocycline) you could buy in a pharmacy or ask your doctor who treats you.
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