Drug Information: Indications, Side Effects, Warnings
Category: Â Antibiotics
Generic Duricef used to treat many different types of infections caused by bacteria. It is in a group of drugs called cephalosporin antibiotics.
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It is Brand(s): Apdil / Cefadur
Manufacturer: Ajanta / Okasa
Therapeutic agents cefadroxil
Nosological classification (ICD-10)
J02.9 Acute pharyngitis, unspecified
J03.9 Acute tonsillitis, unspecified (angina agranulotsitarnoy)
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
L08.9 Local infection of the skin and subcutaneous tissue, unspecified
Infectious myositis M60.0
M65 Synovitis and tenosynovitis
M65.0 Abscess of tendon sheath
M71.0 Abscess of bursa
M71.1 Other infective bursitis
Pharmacological action: anti-bacterial.
— The drug is effective against gram-positive and gram-negative bacteria, Klebsiella, Proteus, Escherichia coli;
— The drug has no effect on the growth of enterococci and enterobacteria.
— Generic Duricef has bactericidal (Bacteriolytic) effect, disrupting the synthesis of peptidoglycan cell wall.
— Generic Duricef rapidly absorbed after oral administration.
-Bakteritsidnaya Blood concentration is maintained for 12 hours;
— Good penetrates all organs and body fluids, except for the CSF and brain tissue.
— 90% Generic Duricef is excreted in the urine unchanged within 20-22 hours.
— Hypersensitivity (including other beta-lactams).
Pregnancy and breast-feeding:
Category effects on the fetus by FDA — B.
At the time of treatment should stop breastfeeding.
Side effects of substance cefadroxil:
Dyspepsia, nausea, vomiting, renal failure, vitamin deficiencies, goiter, candidiasis, pseudomembranous colitis, allergic reactions: skin rash, angioedema, anaphylactic shock.
Other side effects: dyspepsia (diarrhea); irritation of the mucous membranes of the mouth, larynx, pharynx, irritation of the stomach, vagina, rectum and urethra;
-of the skin may be a skin rash, burning, itching, dermatitis / drug reaction; toxic lesions of the hematopoietic system (accompanied by leukopenia, thrombocytopenia, granulocytopenia and agranulocytosis, aplastic or hypoplastic anemia), and sometimes — liver and kidneys;
-patients reported visual and auditory hallucinations;
-hearing loss and vision;
Set individually. It is necessary to take into account the severity and localization of infection susceptibility. If ingestion in adults and children weighing more than 40 kg Cefadroxil used in an average dose: of 1-2 g / day, 1-2 reception. For children weighing less than 40 kg — 25-50 mg / kg / day (Preferably in the form of slurry) used 1-2 reception. The course of treatment is 7-14 days. The minimum duration of the treatment of infectious and inflammatory diseases caused by beta-hemolytic streptococcus group A, is 10 days.
For patients with impaired renal excretory function single dose — 500 mg, the intervals between doses is determined depending on the values â€‹â€‹of QA: QA 0-10 ml / min — 36 hours; QC at 10-25 ml / min — 24 hours; QC at 25-50 ml / min — 12 hr.
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